Description
Latin name
GALAVIT
Packaging
100 ml (5pcs) – packs of cardboard.
Pharmacological action
Immunomodulating drug with anti-inflammatory effect.
The mechanism of action is associated with the ability to influence the functional and metabolic activity of macrophages. In inflammatory diseases, it reversibly (for 6-8 hours) inhibits the excessive synthesis of tumor necrosis factor, interleukin-1 and other pro-inflammatory cytokines, reactive oxygen species by hyperactivated macrophages, which determine the degree of inflammatory reactions, their cyclicity, and also the severity of intoxication. Normalization of the functional state of macrophages leads to the restoration of antigen-presenting and regulatory functions of macrophages, and a decrease in the level of autoaggression.
The drug stimulates the bactericidal activity of neutrophilic granulocytes, enhancing phagocytosis and increasing the nonspecific resistance of the body to infectious diseases.
The main pharmacological effects are observed within 72 hours.
Indications
As an immunomodulator and anti-inflammatory agent in the complex treatment of immunodeficiency in adults and adolescents over 12 years of age: infectious intestinal diseases accompanied by intoxication and / or diarrhea
peptic ulcer disease and duodenal ulcer srdlirp virus herpes
diseases caused by human papillomavirus (HPV)
infectious and inflammatory diseases of the urogenital tract (ure rit chlamydia and trichomonas etiology, chlamydial prostatitis, acute and chronic oophoritis, chronic endometritis)
purulent-inflammatory diseases of the pelvic organs
postoperative rehabilitation of patients with uterine fibroids
complications of the postoperative period in patients of reproductive age
purulent surgical diseases (burn lesions, chronic osteomyelitis, gangrenous peritenitis gaprenitis c) -septic complications and their prevention (including in cancer patients)
chronic recurrent furunculosis, erysipelas of
asthenic states, neurotic and somatoform disorders, decreased physical performance (including athletes)
mental, behavioral and post-withdrawal disorders with alcohol and drug dependence
inflammatory diseases of the mucous membrane of the mouth and throat, periodontal diseases
frequent recurrent diseases of the respiratory tract and ENT organs of bacterial and viral etiology (including frequent acute respiratory viral infections, bronchitis, pneumonia, chronic tonsillitis , chronic otitis media, chronic adenoiditis) and their prevention.
Contraindications
Pregnancy.
Lactation.
Individual intolerance.
Use during pregnancy and lactation
The drug is contraindicated in pregnancy and lactation.
Composition
1 vial
aminodihydrophthalazinedione sodium dihydrate 50 mg
-100 mg
Dosage and administration
The dosage regimen and duration of therapy are set individually depending on the nature, severity and duration of the disease.
For the preparation of a solution for intramuscular injection, a powder preparation for the preparation of an injection solution is diluted in 2 ml of water for injection or in a 0.9% sodium chloride solution.
Adults
For acute intestinal infections accompanied by diarrhea: the initial single dose is 200 mg once. Then the drug is administered at a dose of 100 mg 2 times / day until the symptoms of intoxication are relieved. A subsequent continuation of the course of 100 mg with an interval of 72 hours is possible. The course is 20-25 injections.
For peptic ulcer of the stomach and duodenum: in the acute period – 2 days, 200 mg 1 time / day, then 100 mg every 72 hours. A course of 15-25 injections. In the chronic period – for 5 days, 100 mg 1 time / day, then – 100 mg after 72 hours. Course – 20 injections.
In case of viral hepatitis of various etiologies: in the acute period of the disease, the initial dose is 200 mg once, then 100 mg 2 times / day until the symptoms of intoxication and inflammation are relieved. The subsequent continuation of the course of therapy at a dose of 100 mg with an interval of 72 hours. The course is 20-25 injections.
In case of chronic recurrent herpetic infection: the drug is prescribed 100 mg daily for 5 injections, then 100 mg every other day for 15 injections.
For diseases caused by HPV: the drug is prescribed for 5 days at 100 mg 1 time / day, then at 100 mg every other day. The course is 20 injections.
For urogenital infections (chlamydial and trichomonas urethritis, chlamydial prostatitis): the drug is prescribed 100 mg 2 times / day for 1 day, then they switch to 100 mg every other day. The course is 10-15 injections, depending on the severity of the pathological process.
With salpingoophoritis, endometritis: in the acute period, the drug is prescribed for 2 days at 200 mg 1 time / day, then at 100 mg with an interval of 72 hours. The course is 20 injections. In the chronic period, the drug is prescribed for 5 days at 100 mg 1 time / day, then 100 mg every 72 hours. The course is 20 injections.
In acute and chronic PID: in the acute period, the drug is prescribed for 1 day, 200 mg 1 time / day, then for 3 days, 100 mg daily, then 100 mg every other day 5 injections. The course is 20 injections. In the chronic period, the drug is prescribed for 5 days, 100 mg 1 time / day, then 100 mg every 72 hours. The course is 20 injections.
For postoperative rehabilitation of patients with uterine myoma and complications of the postoperative period in patients of reproductive age: the drug is prescribed for 5 days at 100 mg 1 time / day, then at 100 mg every other day. The course is 15 injections.
For the prevention and treatment of surgical complications in the preoperative and postoperative period (including in cancer patients): the drug is prescribed 100 mg 1 time / day. Before surgery, 5 injections, after surgery, 100 mg every other day and 5 injections with an interval of 72 hours. In severe cases of the disease, the initial dose is 200 mg 1 time / day or 100 mg 2 times / day. The course is 20 injections.
In case of chronic recurrent furunculosis, erysipelas: appoint 100 mg of the drug 1 time / day for 5 days, then 100 mg every other day. The course is 20 injections.
For asthenic conditions, neurotic and somatoform disorders, for mental, behavioral and post-withdrawal disorders, alcohol and drug addiction: the drug is prescribed for 5 days at 100 mg 1 time / day, then at 100 mg after 72 hours. The course is 15- 20 injections.
To increase physical performance: the drug is prescribed 100 mg every other day 5 injections, then 100 mg every 72 hours. The course is up to 20 injections.
For inflammatory diseases of the oral mucosa and pharynx, periodontal disease: initial dose of 100 mg daily 5 injections, then 100 mg every 72 hours. Course – 15 injections.
For children over the age of 6
For purulent surgical diseases (including burn injuries, recurrent furunculosis, chronic osteomyelitis, gangrenous appendicitis with amentitis, peritonitis, purulent pleurisy): the drug is prescribed for children aged 6 to 11 years – 1 injection of 50 mg 1 time / day for 5 days, then 1 injection of 50 mg every other day for 10-15 days . The course is 10-15 injections. For children aged 12 to 18 years, treatment is carried out according to the same scheme in the form of a / m injection of 100 mg.
For dressings, topical application of Galavit in the form of dressings with sterile wipes moistened with a 1% solution of Galavit in water for injection (in dressings with a talker or water-soluble ointment dressings) is desirable.
With frequent recurrent diseases of the respiratory tract and ENT organs of bacterial and viral etiology (frequent acute respiratory viral infections, bronchitis, pneumonia, chronic tonsillitis, chronic otitis media, chronic adenoiditis) for children aged 6 to 11 years, the drug is prescribed 1 injection of 50 mg 1 time / day for 5 days, then 50 mg 1 time / day every other day for 10-15 days. The course is 10-15 injections. For children aged 12 to 18 years, treatment is carried out according to the same scheme in the form of a / m injection of 100 mg.
Side effects
Possibly: an allergic reaction.
Drug Interaction
No clinically relevant interaction of Galavit ® with other medicinal products has been established.
Overdose
There have been no reports of overdoses of Galavit to date.
Storage conditions
Keep out of the reach of children, in a dry, dark place at a temperature of 15 ° to 25 ° C.
Expiration
4 years.
Deystvuyuschee substances
Amynodyhydroftalazyndyon sodium
Conditions of supply of pharmacies
Prescription
dosage form
Selwim, Russia
