Description
Release form
Gel for external use 2.5%
40 g
packaging
Pharmacological action of
Baziron AS has high antimicrobial activity against Propionibacterium acnes and Staphylococcus epidermidis, has comedonolytic and anti-inflammatory effects, improves tissue oxygenation, inhibits sebum production in the sebaceous glands, absorbs excess sebaceous secretion and moisturizes the skin.
Benzoyl peroxide, being a powerful oxidizing agent, has a strong bactericidal effect on microorganisms, while microorganisms are not able to produce strains resistant to benzoyl peroxide.
In an in vivo study, seeding showed that growth inhibition of Propionibacterium acnes by 94% was observed on day 7, and on day 15 by 97-99%.
The anti-inflammatory effect of benzoyl peroxide is based on the inactivation of free radicals in the focus of inflammation and inhibition of free fatty acids.
The basis of the preparation is represented by the acrylate copolymer / glycerin complex, which provides controlled adsorption of excess sebum and the gradual release of glycerin to soften and moisturize the skin.
Indications
Acne.
Contraindications
– children under 12 years of age
– hypersensitivity to the components of the drug.
Use during pregnancy and lactation
Use of Baziron AC gel during pregnancy and breastfeeding is possible when the intended benefit to the mother outweighs the potential risk to the fetus.
Composition of
1 g of gel contains benzoyl peroxide 25 mg
excipients:
acrylate copolymer,
poloxamer 182,
carbomer 940 (carbopol 980), srdlkid sulfide, sodium sulfide, sodium sulfide ,
sodium hydroxide,
distilled water.
Dosage and administration
Gel should be applied to a clean and dry surface of the affected skin 1 or 2 times / day (morning or evening). The course of treatment is 3 months.
The therapeutic effect develops 4 weeks after the start of the drug. Persistent improvement occurs after 3 months of therapy.
Baziron AS is indicated for the treatment of mild to moderate acne with a predominance of pustular elements as monotherapy, and for moderate acne also in combination with other local (retinoids) and systemic (antibiotics, antiandrogens for oral administration).
If necessary, a second course of treatment is possible.
Side effects
In rare cases, local irritation (redness, peeling, dry skin, burning sensation).
In such cases, it is recommended to reduce the frequency of use.
In rare cases, allergic contact dermatitis may occur.
Drug Interaction
There is currently no information on the drug interaction of the drug Basiron AC, used as indicated and recommended doses, with other medicinal products for external and systemic use.
Overdose
Symptoms: Severe irritation at the site of application may occur if a large amount of the preparation is accidentally applied to the skin.
Treatment: The drug should be discontinued and symptomatic therapy should be given.
Storage conditions
The drug should be stored at a temperature not exceeding 25 ° C.
Expiration
3 years.
pharmacy over-the-counter conditions
Laboratory alderma, France
