Description
Packing
30 pcs.
Pharmacological action
Folacin – a vitamin preparation. Vitamin of group B. Folic acid in the body is converted to tetrahydrofolic acid, as a coenzyme involved in various metabolic processes, and necessary for the normal maturation of megaloblasts and the formation of normoblasts. With a deficiency of folic acid, a megaloblastic type of hematopoiesis develops. Folacin stimulates erythropoiesis, participates in the synthesis of amino acids (including methionine, serine, glycine), nucleic acids, purines, pyrimidines, in the exchange of choline, histidine. During pregnancy, it performs a protective function in relation to the action of teratogenic and fetal damaging factors. Folacin contributes to the normal maturation and functioning of the placenta.
Indications
– Treatment and prevention of folic acid deficiency due to unbalanced or malnutrition
– Treatment and prevention of anemia due to folic acid deficiency (macrocytic hyperchromic anemia, anemia and leukopenia caused by drugs, mesemia radiation, and ionizing radiation sideroblastic anemia in elderly patients, anemia associated with diseases of the small intestine, spru and malabsorption syndrome)
– treatment and prevention of anemia pr during pregnancy and lactation (breastfeeding)
– to prevent the development of congenital malformations (neural tube defects) in the fetus
– with prolonged use of folic acid antagonists (methotrexate or sulfamethoxazole-trimethoprim combination), anticonvulsant therapy (phenytoin, primidone, phenobarbital).
Contraindications
Hypersensitivity to the components of the drug folacin
pernicious anemia
malignant neoplasms
cobalamin deficiency.
Special Decreemania
Hemodialysis patients require elevated amounts of folic acid.
With prolonged use of folic acid, especially in high doses, a decrease in the concentration of vitamin B12 in the blood is possible.
Long-term use of the drug is recommended to be combined with vitamin B12 (cyanocobalamin).
Composition
1 tab. contains: folic acid 5 mg,
excipients: lactose monohydrate, povidone, crospovidone, microcrystalline cellulose, magnesium stearate
Dosage and administration of
folacin is administered orally.
For the treatment of megaloblastic anemia due to folic acid deficiency: 5 mg per day for 4 months, for prevention – 2.5 mg per day.
For the prevention and treatment of macrocytic anemia with malabsorption, inflammatory bowel disease and unbalanced or malnutrition – 15 mg per day, for patients with sprue disease – 5-15 mg per day.
To prevent the development of neural tube defects in the fetus, 2.5 mg per day for 4 weeks before the expected pregnancy. Reception continues during the first trimester of pregnancy.
Higher maintenance doses of folacin may be given to patients with alcoholism, as well as patients with chronic infections and taking anticonvulsants.
Side effects
From the digestive system: anorexia, nausea, bloating, bitterness in the mouth.
Allergic reactions: skin rashes, itching, erythema, bronchospasm.
Storage conditions
In the dark place at a temperature of no higher than 25 ° C.
active substance
Folate
The dosage form of
tablet
Indications
Hypovitaminosis, Inadequate nutrition, Anemia
Jadran-Galensky Laboratories a.o., Croatia
