Description
Release form
Intramuscular solution and solvent.
Packaging
6 ampoules complete with solvent.
Indications
– Primary and secondary osteoarthritis.
– Spondylarthrosis.
Contraindications
– Individual hypersensitivity to glucosamine, lidocaine hydrochloride and other components of the drug.
– Phenylketonuria.
Due to the presence of lidocaine in the preparation, it is contraindicated in:
– Cardiac conduction disorders.
– Acute heart failure.
– A history of epileptiform seizures.
– Severe impairment of liver and kidney function.
– During pregnancy.
– During lactation.
– In children under 12 years old.
Precautions:
– Chronic heart failure.
– Arterial hypotension.
– Bronchial asthma.
– Diabetes mellitus.
– Intolerance to seafood (shrimp, shellfish) – the likelihood of developing allergic reactions to the drug increases.
Special instructions
If you are intolerant to seafood (shrimp, shellfish), the likelihood of allergic reactions increases with the use of Elbona.
Composition
The kit contains:
Solution A – in 2 ml of the solution for intramuscular injection contains: glucosamine sodium sulfate chloride 502.5 mg (which corresponds to the content of: glucosamine sulfate 400 mg, sodium chloride 102.5 mg).
Excipients: trometamol to pH 2.0-3.0, lidocaine hydrochloride 10 mg, water d / and up to 2 ml.
Solution B (solvent) – 1 ml of the solution contains: diethanolamine 24 mg, water for injection up to 1 ml.
Dosage and Administration
Intramuscularly! The drug is not intended for intravenous administration. Before use, mix solution B (solvent) with solution A (drug solution) in one syringe. The prepared solution is injected IM 3 ml (solutions A + B) 3 times a week for 4-6 weeks.
Side effects
Drug tolerance is good.
In some cases, possible: flatulence, diarrhea, constipation, allergic reactions (urticaria, pruritus).
Due to the content of lidocaine in the preparation, the following are possible: nausea, vomiting, drowsiness, diplopia, headache, dizziness, numbness of the tongue and oral mucosa, tremors, euphoria, disorientation, impaired cardiac conduction, anaphylactic reactions.
Drug Interactions
Compatible with NSAIDs, paracetamol and GCS. Cimetidine and propranolol reduce hepatic clearance of lidocaine (a decrease in metabolism due to inhibition of microsomal oxidation and a decrease in hepatic blood flow) and increase the risk of toxic effects. When administered with aimalin, phenytoin, verapamil, quinidine, amiodarone, an increase in the negative inotropic effect is possible. Co-administration with beta-blockers increases the risk of developing bradycardia. Cardiac glycosides weaken the cardiotonic effect. Curare-like drugs enhance muscle relaxation. Procainamide with simultaneous use with lidocaine increases the risk of central nervous system excitation, hallucinations.
With the simultaneous administration of sleeping pills and sedatives, it is possible to increase their inhibitory effect on the central nervous system. With the on / in the introduction of hexobarbital or thiopental sodium against the background of the action of lidocaine, respiratory depression is possible. Potentiates the effects of MAO inhibitors. With simultaneous use with polymyxin B, it is possible to increase the inhibitory effect on neuromuscular transmission, therefore, in this case, it is necessary to monitor the patient’s respiratory function. Possible decrease in the effectiveness of hypoglycemic drugs, doxorubicin, teniposide, etoposide.
Storage conditions
Store in a dry, dark place at a temperature of no higher than 25 ° C.
Expiration
2 years.
Active ingredient
Glucosamine
Le drug form
solution for injection
