Description
Latin name
Tiolepta
Release form
Tablets.
Packing
30 pcs
Pharmacological action of
THIOLEPT:
Thioctic acid (alpha lipoic acid) – an endogenous antioxidant (binds free radicals), is formed in the body during the oxidative decarboxylation of alpha keto acids.
As a coenzyme of mitochondrial multienzyme complexes, it participates in the oxidative decarboxylation of pyruvic acid and alpha-keto acids. By the nature of the biochemical action, it is close to the B vitamins.
Improves trophic neurons. It has hepatoprotective, hypolipidemic, hypocholesterolemic, hypogpicemic effect. Helps reduce blood glucose and increase liver glycogen content, as well as reduce insulin resistance.
is involved in the regulation of carbohydrate and lipid metabolism, stimulates cholesterol metabolism, improves liver function.
Indications
Diabetic polyneuropathy.
Alcoholic polyneuropathy.
Contraindications
Hypersensitivity to the components of the drug.
Pregnancy, the period of breastfeeding (there is no sufficient experience with the use of the drug).
Children under 18 years of age (efficacy and safety of use not established).
Lactose intolerance, lactase deficiency, glucose-galactose malabsorption.
Special instructions
Patients taking the drug Tilepta ® should refrain from drinking alcohol.
In patients with diabetes, constant monitoring of blood glucose concentration is necessary, especially at the initial stage of therapy. In some cases, it is necessary to reduce the dose of insulin or an oral hypoglycemic drug to avoid the development of hypoglycemia.
g47 sdlfp 299 composition Composition
Active ingredient: thioctic acid (alpha lipoic acid) 600 mg.
Excipients: calcium stearate, potato starch, silicon dioxide colloidal (aerosil), croscarmellose sodium (primellose), lactose (milk sugar), castor oil, povidone (collidone 30), microcrystalline cellulose.
Dosage and Administration
Inside.
Prescribe 600 mg 1 time per day.
Tablets are taken on an empty stomach, approximately 30 minutes before the first meal, without chewing and drinking a small amount of liquid.
The duration of the course of treatment is determined by the doctor.
Side effects
Typically, Tiolept ® is well tolerated. Possible dyspepsia, including nausea, vomiting, heartburn. In some cases, the development of skin allergic reactions (urticaria) is possible. Hypoglycemia may develop (due to improved glucose uptake).
Drug interaction
With the simultaneous administration of thioctic acid and cisplatin, a decrease in the effectiveness of cisplatin is noted.
Thioctic acid binds metals, therefore it should not be prescribed simultaneously with preparations containing metals (for example, iron, magnesium, calcium) – the interval between doses should be at least 2 hours.
With the simultaneous use of thioctic acid and insulin or oral hypoglycemic drugs their effect may be enhanced.
Ethanol and its metabolites weaken the effect of thioctic acid.
Overdose
Symptoms: headache, nausea, vomiting.
Treatment: carrying out symptomatic therapy. There is no specific antidote.
Storage Conditions
Store in a dry, dark place at a temperature not exceeding 25 ° C.
Shelf life
2 years.
Deystvuyushtee substance
Tioktovaya Chisloth
otpuska IZ
pharmacy prescription
dosage form
tablets
Possible product names
TIOLEPTA 0.6 N30 TABLE P / O
Tilept 600mg Tab. p / pl / rev X30 (R)
Tieolept 600mg No. 30
TIOLEPTA 600MG. No. 30 TAB. P / O / KANONFARMA /
Tialepta tablet p / o 600mg x 30
Kanonfarma, Russia
