Description
Release form
Capsules.
Packing
30 pcs.
Pharmacological action
Furamag – an antimicrobial agent with a wide spectrum of action, belonging to the group of nitrofurans.
Furamagu resistance develops slowly and does not reach a high degree.
Active against gram-positive cocci: Streptococcus spp., Staphylococcus spp. gram-negative rods: Escherichia coli, Salmonella spp., Shigella spp., Proteus mirabilis, Klebsiella spp., Enterobacter spp. protozoa: Lamblia intestinalis and other antibiotic-resistant microorganisms.
In relation to Staphylococcus spp., Escherichia coli, Aerobacter aerogenes, Leuconostoc citrovorum, Proteus mirabilis, Proteus morganii Furamag ®, in comparison with other nitrofurans, is more active.
Against most bacteria, the bacteriostatic concentration is from 1: 100,000 to 1: 200,000. The bactericidal concentration is about 2 times greater.
Under the influence of nitrofurans in microorganisms, the respiratory chain and the tricarboxylic acid cycle (Krebs cycle) are suppressed, as well as the inhibition of other biochemical processes of microorganisms, resulting in the destruction of their membrane or cytoplasmic membrane.
As a result of the action of nitrofurans, microorganisms produce less toxins, and therefore an improvement in the general condition of the patient is possible even before the marked suppression of microflora growth. Nitrofurans activate the body’s immune system: increase the titer of complement and the ability of leukocytes to phagocytize microorganisms. Furazidine in therapeutic doses stimulates leukopoiesis.
Indications
Infections caused by susceptible microorganisms:
– urogenital infections (acute cystitis, urethritis, pyelonephritis)
– gynecological infections
– infections of the skin and soft tissues
– severe infections during surgical treatment with
. including cystoscopy, catheterization).
Contraindications
– severe chronic renal failure
– pregnancy
– lactation (breastfeeding)
– children under 3 years of age (for this dosage form)
– hypersensitivity to drugs of the nitrofuran group.
Use with caution in case of glucose-6-phosphate dehydrogenase deficiency in the neonatal period.
Special instructions
To reduce the likelihood of side effects, Furamag ® is washed down with plenty of fluids.
If side effects occur, the drug should be discontinued (toxic effects are more likely to occur in patients with reduced renal excretory function).
The patient should inform the doctor of any side effects arising during treatment with the drug.
During the treatment period, the patient is advised to refrain from drinking alcohol, as it is possible to increase side effects.
The influence of Furamaga on the ability to drive vehicles and control mechanisms is not marked.
Composition
Furazidine (in the form of potassium salt) 25 mg.
Excipients: basic magnesium carbonate, potassium carbonate, talc.
Dosage and administration of
The drug should be taken orally after a meal.
Adults are prescribed 50-100 mg 3 times / day.
Children over 3 years of age are prescribed 25-50 mg (not more than 5 mg / kg of body weight) 3 times / day.
The course of treatment is 7-10 days. If necessary, repeat the treatment should take a break for 10-15 days.
For the prevention of infection (including during urological operations, cystoscopy, catheterization), the drug is prescribed for adults at 50 mg, for children at 25 mg once 30 minutes before the procedure.
If you skip taking the drug, the next dose should be taken at the usual time. Do not take a double dose to compensate for the missed dose.
Side effects
From the digestive system: rarely – nausea, vomiting, loss of appetite, impaired liver function.
From the side of the central nervous system and peripheral nervous system: rarely – headache, dizziness, polyneuritis.
Allergic reactions: rarely – skin rash (including papular rashes).
Furamag ® has low toxicity.
Drug Interactions
Furamag ® should not be used simultaneously with ristomycin, chloramphenicol, sulfonamides (increased risk of inhibition of hematopoiesis).
It is not recommended to prescribe drugs that can acidify urine (including ascorbic acid, calcium chloride) at the same time as nitrofurans.
Overdose
Symptoms: manifestations of a neurotoxic nature, ataxia, tremor.
Treatment: Drink plenty of fluids. To stop acute symptoms, antihistamines (diphenhydramine) are used. For the prevention of neuritis, it is possible to prescribe vitamins (thiamine bromide).
Storage conditions
At a temperature not exceeding 25 ° C.
The Expiration of
is 3 years.
Active substance
Fu azidin
Terms leave through pharmacies
In retseptu
Dosage form
capsule
Olainfarm, Latvia
