Description
Latin name
LECROLYN
Release form
lecrolin. Eye drops
Packing
10 ml – plastic dropper bottle (1) – packs of cardboard.
Pharmacological action
Antiallergic drug, mast cell membrane stabilizer. It prevents the degranulation of mast cells and the release of histamine, bradykinin, leukotrienes (including a slow-reacting substance) and other biologically active substances from them.
The drug is most effective for prophylactic use.
The full clinical effect of allergic eye diseases is achieved after a few days or weeks of treatment with the drug.
Pharmacokinetics
Absorption
When applying eye drops, the absorption of cromolyn sodium through the mucous membrane of the eye is negligible.
Systemic bioavailability is less than 0.1%.
Withdrawal of
T1 / 2 is 5-10 minutes.
Indications
allergic conjunctivitis
allergic keratitis
keratoconjunctivitis
irritation of the mucous membrane of the eyes, due to allergic reactions (environmental factors, occupational hazards, household chemicals, cosmetics, ophthalmic preparations, plant pollen and pet dander).
Contraindications
children under 4 years of age
hypersensitivity to the components of the drug.
Use during pregnancy and lactation
During pregnancy and during lactation (breastfeeding), the drug should be used with caution and only if the intended benefit to the mother outweighs the potential risk to the fetus or infant.
Composition
1 ml eye drops 2% contains:
Active ingredients
Cromoglycic acid (in the form of disodium salt) 20 mg.
Excipients
Benzalkonium chloride (40 mcg), boric acid, disodium edetate, d / i water.
Dosage and administration
The drug is prescribed 1-2 drops in each conjunctival sac 4 times / day.
In seasonal allergic conjunctivitis, treatment should be started immediately after the onset of the first symptoms or used prophylactically before the onset of the pollen onset season. Treatment is continued throughout the flowering season or longer if symptoms persist.
Side effects
From the side of the organ of vision:> 1/100 – short-term burning sensation, local eye irritation and rapidly passing violation of the clarity of visual perception.
Other: <1/10 000 - allergic reactions. Drug Interaction No negative symptoms of interaction of cromoglycic acid with other drugs were noted. The use of cromoglycic acid may reduce the need for ophthalmic preparations containing ACS. Overdose Overdose is unlikely when used topically. Experimental studies have shown that local and systemic toxicity of cromoglycic acid is very low. Symptoms: nausea may occur. Treatment: conducting symptomatic therapy. Storage conditions The drug should be stored out of the reach of children, protected from light at a temperature of 15 ° to 25 ° C. Expiration 3 years. After opening the dropper bottle, the Expiration is 1 month. Deystvuyuschee substances Kromohlytsyevaya acid Pharmacy terms of delivery OTC dosage form dosage form eye drops Santen, France
