Description
Latin name
ISOPRINOSINE
Release form
Tablets are white or almost white, oblong, biconvex, with a slight amine odor, with a risk on one side.
Packing
10 pcs – blisters (2) – packs of cardboard.
Indications
Influenza
ARVI.
Herpes simplex virus infections of the 1st, 2nd, 3rd and 4th types: Genital and labial herpes.
Herpetic keratitis.
Herpes zoster.
Chicken pox.
Infectious mononucleosis caused by the Epstein-Barr virus.
Cytomegalovirus infection.
Heavy current.
Papillomavirus infection: Larynx / vocal cord papillomas (fibrotic type).
Papillomavirus genital infection in men and women.
Warts.
Molluscum contagiosum.
Contraindications
Gout urolithiasis arrhythmia chronic renal failure children under 3 years of age (body weight up to 15-20 kg) pregnancy lactation (breastfeeding) hypersensitivity to the drug.
Use during pregnancy and lactation
It is not recommended to use the drug during pregnancy and during lactation, since the safety of use has not been investigated.
Composition
1 tab.
inosine pranobex 500 mg.
Excipients:
mannitol,
wheat starch,
povidone,
magnesium stearate.
Dosage and administration
Take orally.
Adults: 500 mg to 4 g / day.
Children 3 to 12 years of age: 50 mg / kg / day.
In both adults and children, with severe infectious diseases, the dose can be individually increased to 100 mg / kg body weight / day, divided into 4-6 receptions. The maximum daily dose for adults is 3-4 g, for children – 50 mg / kg.
Frequency of administration, course of treatment, frequency of repeated courses depends on the indications, course of the disease, treatment regimen.
Side effects
From the nervous system: often – headache, dizziness, fatigue, feeling ill often – nervousness, drowsiness, insomnia.
From the gastrointestinal tract: often – decreased appetite, nausea, vomiting, epigastric pain infrequently – diarrhea, constipation.
From the hepatobiliary system: often – increased activity of liver enzymes, alkaline phosphatase.
From the skin and subcutaneous fat: often – itching, rash.
From the kidneys and urinary tract: infrequently – polyuria.
Allergic reactions: infrequently – maculopapular rash, urticaria, angioedema.
From the musculoskeletal system: often – joint pain, exacerbation of gout.
Other: often – increased blood urea nitrogen concentration.
Drug Interaction
Immunosuppressants attenuate the immunostimulatory effect of pranobex inosine.
When used concurrently with xanthine oxidase inhibitors (allopurinol) or loop diuretics (furosemide, torasemide, ethacrynic acid), uric acid concentration in the serum may be increased.
Co-administration with zidovudine increases the concentration of zidovudine in blood plasma and lengthens it with T1 / 2. This combination may require a dose adjustment of zidovudine.
When combined, enhances the action of interferon-alpha, antiviral agents acyclovir and zidovudine.
overdose
Isoprinosine overdose has not been reported.
Storage conditions
List B. The drug should be stored out of the reach of children, in a dry, dark place at a temperature not exceeding 25 ° C.
Expiration
5 years.
Deystvuyuschee substances
inosine pranobex
dosage form
drug venal form
tablets
