Description
Release form
Solution for intravenous and intramuscular administration
Packing
3 ampoules of 4 ml.
Pharmacological action
Cholitilin is a nootropic drug. Central cholinostimulator, which contains 40.5% metabolically protected choline.
Provides the synthesis of acetylcholine and phosphatidylcholine in neuronal membranes, improves blood flow and enhances the metabolic processes in the central nervous system, activates the reticular formation. It increases the linear velocity of blood flow, helps to normalize the spatio-temporal characteristics of spontaneous bioelectric activity of the brain, regression of focal neurological symptoms and recovery of consciousness has a positive effect on cognitive and behavioral responses of patients with cerebrovascular diseases (discirculatory encephalopathy and residual effects of cerebrovascular accident).
It has a preventive and corrective effect on the pathogenetic factors of involutional psycho-organic syndrome, reduces cholinergic activity. It stimulates the dose-dependent secretion of acetylcholine under physiological conditions by participating in the synthesis of phosphatidylcholine (membrane phospholipid), improves synaptic transmission, plasticity of neuronal membranes. It does not affect the reproductive cycle and does not have a teratogenic, mutagenic effect.
Pharmacokinetics
Solution: Choline alfoscerate easily penetrates the blood-brain barrier. It is excreted mainly by the lungs in the form of carbon dioxide (85%), as well as by the kidneys and through the intestines (15%).
Indications
In complex therapy for: traumatic brain injury with predominantly stem lesion level (acute period)
cerebrovascular insufficiency
psycho-organic syndrome against degenerative diseases and involutional processes of the brain
multi-infarction dementia.
Contraindications
hypersensitivity
hemorrhagic stroke (acute stage)
pregnancy
breastfeeding
age up to 18 years.
Special instructions
During the treatment period, care must be taken when driving vehicles and engaging in other potentially dangerous activities that require increased concentration of attention and speed of psychomotor reactions.
Composition
1 ml. solution for intravenous and intramuscular administration contains:
active substance: choline alfoscerate polyhydrate (Lipoid GFH 85F) 250 mg
excipients: povidone, water for injection
Dosing and Administration
The drug is administered intramuscularly at a dose of 1 g (1 ampoule) per day or intravenously slowly at 1 g per day for 1520 days. In the future, the transition to the oral form of the drug (capsules) is possible.
Side effects
From the digestive system: constipation, diarrhea, dry oral mucosa, pharyngitis.
From the nervous system: headache, drowsiness, insomnia, aggressiveness, anxiety, nervousness, dizziness.
From the skin: rash, urticaria.
Other: pain at the injection site, increased urination.
Drug interaction
Drug drug interaction not established.
Storage conditions
In a dry, dark place at a temperature of no higher than 25 ° C.
Expiration
2 years.
Deystvuyuschee
substances Choline alfostserat
pharmacy terms and conditions for prescription
Form of Treatment
simply entails dlya inaektsiy and infusing
Company Deco, Russia
