Description
Pharmacological action
The drug blocks the passage of calcium ions through the cell membrane. This helps to reduce their presence in the depot.
Means reduces tinnitus, reduces headache. This happens because the property of the drug to improve the state of blood vessels helps normalize cerebral circulation.
The tone of smooth muscles of arterioles decreases. Peripheral and coronary circulation improves, tissues are supplied with blood more fully. Possible postischemic hyperemia.
Vasoconstrictors of a biogenic nature after taking the drug do not have an adequate reaction from the body, because cinnarizine is able to suppress them. The ability of cinnarizine to exhibit moderate antihistamine activity also works to improve blood circulation.
The ingredients of the drug have an effect on blood cells, reduce its viscosity. Red blood cells under the influence of the agent improve the condition of the membranes, increasing their elasticity. The drug helps cells survive in conditions of oxygen deficiency.
Indications
The drug is prescribed for the following diseases: peripheral blood circulation worsens and it manifests as: Raynaud’s disease,
obliterating thromboangiitis,
intermittent claudication,
diabetic angiopathy,
thrombosis, srdlrd, srd stroke,
senile dementia,
discirculatory encephalopathy,
prevention of migraine attacks,
state after strokes,
prevention of kinetoses,
head injuries ,
vestibular disorders.
Contraindications
– hypersensitivity
– pregnancy
– lactation
– children under 5 years of age.
Caution for Parkinson’s disease.
Special instructions
Patients with Parkinson’s disease are prescribed the drug only when the benefits of cinnarizine treatment outweigh the potential worsening of the underlying disease.
At the beginning of treatment, it can cause drowsiness, so taking alcohol and the simultaneous use of CNS depressants requires caution.
Due to the antihistamine effect, cinnarizine should be discontinued 4 days before an allergic skin test. Cinnarizine may affect the result of anti-doping control of athletes (false positive).
In case of lactose intolerance, it should be noted that 1 tablet contains 175 mg of lactose.
Effect on the ability to drive a car and other operating mechanisms
Drowsiness may develop, especially at the beginning of treatment, therefore, caution should be exercised when driving vehicles and engaging in other potentially hazardous activities that require an increased concentration of attention and speed of psychomotor reactions. With prolonged use, a control laboratory examination of the liver, kidneys, and peripheral blood is recommended.
Ingredients
Active ingredient: 25 mg cinnarizine
Additional ingredients: povidone,
lactose,
magnesium starch starch.
Dosage and Administration
Inside, after meals.
With cerebrovascular insufficiency – 25 mg 3 times / day.
In case of peripheral circulation disorder – 50-75 mg 3 times / day.
For vestibular disorders – 25 mg 3 times / day.
The maximum recommended dose should not exceed 225 mg (9 tablets) per day. The course of treatment is from several weeks to several months.
In case of kinetosis (traffic sickness): adults – 25 mg half an hour before the road (if necessary, take 25 mg again after 6 hours), for children from 5 years – 1/2 dose recommended by adults.
With high sensitivity to the drug, treatment begins with 1/2 dose, increasing it gradually.
Side effects of
From the nervous system: drowsiness, fatigue, headache, extrapyramidal disorders (tremor of the extremities and increased muscle tone, hypokinesia), depression.
From the digestive system: dry mouth, epigastric pain, dyspepsia, cholestatic jaundice.
From the skin: sweating, the development of lupus-like syndrome, lichen planus (extremely rare), skin rash.
Other: allergic reactions, weight gain.
Overdose
Symptoms: increased severity of side effects, decreased blood pressure, vomiting, coma.
Treatment: there is no specific antidote, gastric lavage, activated charcoal intake, symptomatic therapy.
Storage conditions
The drug should be stored in a dry, dark place and out of the reach of children.
Expiration
2 years
Deystvuyuschee substances
cinnarizine
dosage form
tablets
Prescribing
Adult prescribing, Children15 months doctor, Children by doctor’s appointment, Children over 5 years
Indications
From disease Meniere, From effects of stroke, from concussion and other traumatic brain injuries, thrombophlebitis, from vascular damage in diabetes mellitus, from trophic ulcers
Anzhero-HFZ, Russia
