Description
Description
White or creamy tint.
Latin name
Streptocidum
Release form
Ointment (liniment) for external use 5%.
Pharmacological action
Antimicrobial bacteriostatic agent, sulfonamide. The mechanism of action of the drug is due to competitive antagonism with para-aminobenzoic acid (PABA), inhibition of dihydropteroate synthase, impaired synthesis of tetrahydrofolate acid, necessary for the synthesis of purines and pyrimidines. Active against Staphylococcus spp., Streptococcus spp., Including S.pyagenes, S. pneumoniae, Legionella spp., Brucella spp., Escherichia coli, Shigella spp., Klebsiella spp., Proteus spp., Salmonella spp., Serratia spp., Calymmatobacterium granulomatis, Vibrio cholerae, Clostridium perfringens, Bacillus anthracis, Nocardia asteroids, Corynebacterium diphtheriae, Yersinia pestis, Chlamydia spp., Actinomyces israelii, Toxoplasma gond When applied to the skin, it contributes to the rapid healing of wounds and epithelization of erosion.
Indications
Infected wounds of various etiologies, burns (I-II art.), folliculitis, boils, carbuncles, acne vulgaris, impetigo, erysipelas and other purulent-inflammatory processes of the skin.
Contraindications
Hypersensitivity to the drug, anemia, renal / hepatic insufficiency, congenital deficiency of glucose-6-phosphate dehydrogenase, azotemia, porphyria, pregnancy, lactation. With care. Children under 3 months.
Use during pregnancy and lactation
Contraindicated for use in I and II trimesters of pregnancy and lactation
Special instructions
An abundant alkaline drink is recommended in the treatment of extensive skin lesions. Influence on the ability to drive vehicles and work with mechanisms The drug does not affect the ability to drive vehicles and engage in potentially dangerous activities that require increased concentration of attention and speed of psychomotor reactions.
Composition
1 g of liniment contains: active substance – sodium sulfanilamide (soluble streptocide) – 0.05 g (in terms of 100% substance) excipients: glycerol (distilled glycerin) – 0.30 g, emulsifier No. 1 (Lanette ® SX) – 0.080 g, water (purified water) – up to 1 g.
Dosage and Administration
Externally. Liniment is applied to a gauze dressing, which is applied to the affected area of the dressing is performed after 1-2 days. With a large lesion area, the daily dose of liniment in terms of sulfanilamide should not exceed 6 g in adults (corresponds to 120 g of liniment), 0.6 g in children under 1 year of age (corresponds to 12 g of liniment), 1.8 g in children 1-5 years (corresponds to 36 g of liniment), 3 g in children 5-12 years old (corresponds to 60 g of liniment).
Side effects
Allergic reactions are possible. With prolonged use of large doses – systemic action: headache, nausea, vomiting, dyspepsia, leukopenia, agranulocytosis, crystalluria.
Drug Interaction
Myelotoxic drugs increase the hematotoxicity of the drug.
Overdose
Symptoms: nausea, vomiting, intestinal colic, dizziness, headache, drowsiness, depression, fainting, confusion, blurred vision, fever, hematuria, crystalluria with prolonged overdose – thrombocytopenia, leukopenia, leukopenia, leukopenia.
Treatment: Drinking plenty of water with a random intake of ointment and powder inside – gastric lavage.
Storage Conditions
At a temperature not exceeding 25 C. Keep out of reach of children!
Expiration
4 years. Do not use after the expiry date stated on the pack.
active substance
sulfanilamide
Nizhpharm, Russia
