Description
Packaging
20 pcs.
Pharmacological action
Maalox – antacid.
Pharmacodynamics
The drug neutralizes free hydrochloric acid without causing secondary hypersecretion of hydrochloric acid. Due to the increase in pH when it is taken, the peptic activity of gastric juice decreases. It also has an adsorbing and enveloping effect, due to which the effect of damaging factors on the mucous membrane is reduced.
Pharmacokinetics
Magnesium and aluminum hydroxides are considered topical antacids that are practically not absorbed when taken at recommended doses and, therefore, do not have systemic effects.
Indications
Peptic ulcer of the stomach and duodenum in the exacerbation phase
acute gastroduodenitis
chronic gastroduodenitis with normal or increased secretory function in the exacerbation phase
hernia of the esophageal reflux syndrome some drugs (including NSAIDs, corticosteroids)
discomfort or pain in the epigastrium, heartburn with errors in diet, excessive use of coffee, alcohol, nicotine.
Contraindications
severe renal failure
hypersensitivity to active substances and other components of the drug
hypophosphatemia
fructose intolerance (due to the presence of sorbitol in the preparation)
children and adolescents under 15 years of age.
Use during pregnancy and lactation
Contraindicated in pregnancy and lactation.
Composition
1 tablet contains:
Active substances: magnesium hydroxide 400 mg algeldrate (in the form of hydrated aluminum oxide) 400 mg (equivalent to 200 mg of aluminum oxide)
Excipients: starch with sucrose (confectionery sugar) sorbitol mannitol magnesium stearate peppermint flavoring sucrose sucrose.
Dosage and administration
Inside, absorbable or chewed thoroughly.
Adults and adolescents over 15 years of age – 1-2 tablets 3-4 times a day, 1-2 hours after eating and at night.
In reflux esophagitis, the drug is taken shortly after eating. The maximum number of doses of the drug is 6 times a day. Do not take more than 12 tablets per day. The course of treatment should not exceed 2-3 months. With occasional use (for example, with discomfort after errors in the diet) – 1-2 tablets once.
Side effects of the
Immune system disorders: unknown frequency – hypersensitivity reactions such as pruritus, urticaria, angioedema and anaphylactic reactions.
Disorders from the gastrointestinal tract: infrequently – diarrhea, constipation.
Metabolic and nutritional disorders: unknown frequency – hypermagnesemia, hyperaluminemia, hypophosphatemia (with prolonged treatment or taking high doses, or when taking standard doses with a low phosphate content in food), which can lead to increased bone resorption, hypercalciuria, osteomalacia.
Lekarstvennoe Interaction
With simultaneous standard receiving with Maalox snyzhaetsya vsas vanye antibiotics tetracycline rjada, ciprofloxacin, ofloxacin, digoxin, indometacin, atsetylsalytsylovoy acid (and others salicylates), blockers of histamine H2-receptor, beta-blockers, chlorpromazine, dyflunyzala, isoniazid, fenytoyna, phosphorus-containing drugs.
When used concomitantly, Maalox may increase the level of quinidine in blood plasma, which increases the risk of overdose.
overdose
Symptoms of an acute overdose with a combination of aluminum hydroxide and magnesium salts include diarrhea, abdominal pain and vomiting.
In high-risk patients, taking high doses of the drug can cause or aggravate bowel obstruction or intestinal obstruction.
Treatment: aluminum and magnesium are excreted in the urine. Treatment of acute overdose is carried out with the help of fluid loss and forced diuresis. Patients with renal insufficiency need hemodialysis or peritoneal dialysis.
Storage conditions
Keep out of the reach of children at a temperature not exceeding 25 ° C.
Shelf suitability
3 Year
Deystvuyuschee substances
Alheldrat, magnesium hydroxide
Dosage
dosage form poured form
lozenges
Sanofi-Aventis, France
