Description
Injection form
injection
Packaging
Bottle 400 ml.
Pharmacological action
REMAXOL ® – balanced infusion solution with hepatoprotective action.
Under the influence of the drug, the transition of anaerobic to aerobic processes is accelerated, the energy supply of hepatocytes is improved, macroerg synthesis is increased, the resistance of hepatocyte membranes to lipid peroxidation is increased, the activity of antioxidant enzymes is restored. REMAXOL ® reduces cytolysis, which is manifested in a decrease in indicator enzymes: aspartate aminotransferases, alanine aminotransferases.
REMAXOL ® helps to reduce bilirubin and its fractions, improves the excretion of direct bilirubin in bile. Reduces the activity of hepatocyte excretory enzymes – alkaline phosphatase and gamma-glutamyl transpeptidase, promotes the oxidation of cholesterol into bile acids.
Pharmacokinetics
When administered intravenously, the constituents of the natural components are rapidly distributed in the tissues of the body, utilizing almost instantly. Metabolism products are excreted in the urine and do not accumulate in the body.
Indications
– Dysfunction of the liver due to acute or chronic damage to it: – Toxic hepatitis.
– Alcoholic hepatitis.
– Medicinal hepatitis.
Contraindications
– Individual intolerance to the components of the drug.
– Pregnancy.
– Lactation.
– Children’s age.
Precautions:
– Nephrolithiasis.
– Gout.
– Hyperuricemia.
Special instructions
Non-wetting of the inner surface of the bottle is not a contraindication to the use of the drug.
Ingredients
Active ingredients:
succinic acid ² 5.280 g
meglumine (N-methylglucamine) – 8.725 g
inosine (riboxin) – 2.0 g
methionine – 0.75 g
nicotinamide – 0.25 g
Excipients: sodium chloride – 6.0 g potassium chloride – 0.30 g magnesium chloride hexahydrate (in terms of anhydrous) – 0.12 g sodium hydroxide – 1,788 g water for injection up to – 1,0 l.
Dosage and administration
Remaxol is administered only intravenously in a daily dose from 400 ml to 800 ml for 3-12 days, depending on the severity of the disease. The rate of administration is 40-60 drops (2-3 ml) per minute.
Side effects of
With the rapid introduction of the solution, unwanted reactions may occur: hyperemia of the skin of varying severity, fever, sore throat, dry mouth, which do not require drug withdrawal.
Allergic reactions in the form of an allergic rash and skin itching are possible, which are eliminated by the use of antihistamines.
Rare adverse reactions include nausea, headache, and dizziness.
Due to the activation of aerobic processes in the body, a decrease in glucose concentration and an increase in uric acid in the blood are possible.
Drug interaction
It is not recommended to mix in the same bottle with other medicines for intravenous administration.
Storage conditions
In the dark place at a temperature of 0 to 25 ° C.
Active ingredient
Succinic acid, Meglumine, Riboxin, M ethionine, Nicotinamide
Pharmacy terms
Prescription
Polysan NTFF OOO, Russia
