Description
Release form
Syrup
Packing
Bottle 200 ml.
Pharmacological action
Joset – a combination drug, has bronchodilator, expectorant, mucolytic effect.
– Salbutamol is a bronchodilator, stimulates 2-adrenoreceptors of the bronchi, prevents or relieves bronchospasm.
– Bromhexine is a mucolytic, has an expectorant and mild antitussive effect. It reduces the viscosity of sputum due to the depolarization of acid mucopolysaccharides and stimulation of secretory cells of the bronchial mucosa. Activates cilia of ciliated epithelium, improving sputum discharge.
– Guaifenesin – reduces the surface tension and adhesive properties of sputum, increases the serous component of the bronchial secretion, reduces the viscosity of sputum, activates the ciliary apparatus of the bronchi, facilitates the removal of sputum and promotes the transition of unproductive cough into a productive one.
– Menthol – has an antispasmodic effect, gently stimulates the secretion of bronchial glands, has antiseptic properties, has a calming effect and reduces irritation of the mucous membrane of the respiratory tract.
Indications
Acute and chronic bronchopulmonary diseases accompanied by difficulty in sputum discharge: – bronchial asthma
– chronic bronchitis
– pulmonary emphysema
– COPD
pulmonary pulmonary disease – pulmonary tuberculosis srdlpp – pulmonary pulmonary tuberculosis –
Contraindications
– tachyarrhythmia
– myocarditis
– aortic stenosis
– dekompencirovanny diabetes
– thyrotoxicosis
– glaucoma
– hepatic and / or renal failure
– gastric ulcer and duodenal ulcer in
exacerbation phase – gastric bleeding
– Pregnancy
– the period of lactation (breastfeeding)
– hypersensitivity to the components of the drug Joset.
Caution should be used in patients with diabetes mellitus, arterial hypertension, gastric ulcer and duodenal ulcer history, along with antitussive drugs, non-selective -adrenoreceptor blockers, MAO inhibitors.
Special instructions
Guaifenesin stains urine pink.
It is not recommended to drink the drug with an alkaline drink.
Composition of
5 ml of syrup contains: salbutamol sulfate 1.205 mg, which corresponds to the content of salbam 1 mg, bromhexine hydrochloride 2 mg, guaifenesin 50 mg, menthol (levomenthol) 500 mcg,
excipients: sodium methyl parahydroxybenzoate, sodium propyl parahydroxybenzoate, sucrose, propylene glycol, sodium saccharinate, sorbic acid, glycerol, citric acid monohydrate, sorbitol (non-crystalline yellow, crystallizable, crystalline yellow) .
Dosage and Administration
The drug should be taken orally.
Children under the age of 6 years – 1 tsp. (5 ml) 3 times / day. from 6 to 12 years old – 1-2 tsp. (5-10 ml) 3 times / day.
Adults and children over 12 years old – 2 tsp each. (10 ml) 3 times / day.
Side effects
From the side of the central nervous system: headache, dizziness, increased nervous irritability, sleep disturbance, drowsiness, tremors, cramps.
From the digestive system: nausea, vomiting, diarrhea, exacerbation of peptic ulcer of the stomach and duodenum very rarely – increased activity of hepatic transaminases.
From the cardiovascular system: tachycardia, decreased blood pressure, collapse.
From the urinary system: urine staining pink.
Allergic reactions: skin rash, urticaria, paradoxical bronchospasm.
Drug Interactions
Beta2-Adenomimetic, theophylline and other xanthines with simultaneous use with the drug increase the likelihood of developing tachyarrhythmias.
MAO inhibitors and tricyclic antidepressants enhance the effects of salbutamol, can lead to a sharp decrease in blood pressure.
Diuretics and corticosteroids enhance the hypokalemic effect of salbutamol.
Concomitant use with codeine-containing preparations and other antitussive drugs makes it difficult to discharge liquefied sputum.
Bromhexine, which is part of the drug, promotes the penetration of antibiotics into the lung tissue.
It is not recommended to use simultaneously with non-selective blockers of? -adrenoreceptors.
Overdose
Symptoms: increased manifestations of side effects.
Treatment: symptomatic therapy.
Deystvuyuschee substances
Broyheksyn, Hvayfenyzyn, Salbutamol, Menthol (Levomentol)
Terms and conditions otpuska from
pharmacies Prescription
Unique Pharmaceutical, India
