Description
Pharmacological action
Combined preparation, the action of which is due to its constituent components. It regulates the exchange of calcium and phosphates, reduces resorption and increases bone density, makes up for the lack of calcium and vitamin D3 in the body, enhances the absorption of calcium in the intestines and reabsorption of phosphates in the kidneys, and promotes bone mineralization.
Calcium – is involved in the formation of bone tissue, blood coagulation, in maintaining stable cardiac activity, in the implementation of the processes of transmission of nerve impulses.
Vitamin D3 (colecalciferol) – promotes absorption of calcium in the intestine, the formation and mineralization of bone tissue and tooth tissue.
The use of calcium and vitamin D3 prevents the increase in the production of parathyroid hormone, which is a stimulator of increased bone resorption.
Pharmacokinetics:
Vitamin D3 is absorbed in the small intestine. Calcium is absorbed in ionized form in the proximal small intestine through an active, D-vitamin-dependent transport mechanism.
Indications
Prevention and combination therapy of osteoporosis (menopausal, senile, steroid, idiopathic) and its complications (bone fractures).
Replenishment of calcium and / or vitamin D3 deficiency.
Contraindications
Hypersensitivity to the drug’s components (including lactose intolerance, lactase deficiency, glucose-galactose malabsorption), hypercalcemia, hypercalciuria, calcium nephrourolithiasis, hypervitaminosis, calcitosis, calcitosis, mycosis, calcitosis, calcitosis, calcitosis, , phenylketonuria (contains aspartame), pulmonary tuberculosis (active form), chronic renal failure, children under 3 years old.
Precautions
Pregnancy, lactation.
Use during pregnancy and lactation
During pregnancy, the daily dose should not exceed 1500 mg of calcium and 600 IU of vitamin D3.
Vitamin D and its metabolites may pass into breast milk.
Overdose during pregnancy can lead to a violation of the mental and physical development of the child.
Composition srdlrdp Active ingredients – 500 mg
(as calcium carbonate – 1.250 g)
Kolekal tsiferol – 0.01 mg (400 IU)
(Vitamin D3)
(in terms of 100% colecalciferol)
in the form of a granulate containing: colecalciferol – 0.27%, D, L – alpha-tocopherol – 0.0275%,
medium chain triglycerides – 10, 7%, sucrose – 36%, acacia gum – 22%, corn starch – 27%, calcium phosphate (E341) – 0.5%, water up to 100%)
Excipients:
lactose monohydrate (milk sugar) – 343, 10 mg,
povidone medium molecular weight – 64.30 mg,
polysorbate-80 – 2.90 mg,
potato starch – 8.90 mg,
croscarmellose sodium – 50.20 mg,
citric acid – 3.40 mg,
aspartame (E 951) – 5.90 mg
magnesium stearate – 16.30 mg
orange oil or flavoring orange or peppermint oil or peppermint flavoring – 1.30 mg.
Dosage and administration
Inside, chew or swallow whole, mainly with food, washed down with water.
Adults: in the treatment of osteoporosis – 1 tablet 2-3 times a day, for the prevention of osteoporosis – 1 tablet 2 times a day
To make up for a deficiency of calcium and / or vitamin D3:
Adults and children over 12 years of age – 1 tablet 1-2 times a day.
Children from 3 years to 12 years old – 1 tablet per day or as directed by a doctor.
Side effects
Allergic reactions.
Dyspeptic disorders of the gastrointestinal tract (constipation, flatulence, nausea, stomach pain, diarrhea).
Hypercalcemia and hypercalciuria (elevated levels of calcium in the blood and urine).
Storage conditions
At a temperature not exceeding 25 ° C. Keep out of the reach of children.
Shelf life
3 years.
active substance
Calcium carbonate Kolekaltsiferol
lekarstvennaja form
pills for resorption
