Description
Latin name
Powercort
Release form
Cream for external use.
15 g packaging
Pharmacological action
PAUERKORT – anti-inflammatory, anti-allergic.
Has glucocorticoid activity, more pronounced than that of natural hormones.
It is applied topically (eliminates edema, hyperemia, itching at the site of application).
However, even with topical application, absorption and development of systemic effects is possible.
Metabolized mainly in the liver, a small part – in the kidneys. It is excreted in the urine.
Indications
– psoriasis (except for pustular and common plaque)
– chronic eczema
– lichen planus
– discoid lupus erythematosus
– other skin diseases with other corticosteroids being ineffective.
Contraindications
Hypersensitivity, pink acne and juvenile, perioral dermatitis, bacterial, viral and fungal infections of the skin, genital and perianal itching, pregnancy and lactation, children (up to 1 year).
Lotion – scalp infections.
Use during pregnancy and lactation
GCS for local use should not be used during pregnancy for a long time in large doses.
The safety of clobetasol propionate during lactation has not been established.
Composition of
100 g of cream contains:
Active ingredient:
– clobetasol propionate
Excipients:
paraffin (soft, white)
paraffin liquid cetomacrogol
sodium phosphate monohydrate
sodium phosphate dihydrate
butylhydroxytoluene
methyl parahydroxybenzoate
propylpropyl
arahydroxybenzoate propylene glycol
purified water.
Dosage and administration
Externally, apply a thin layer to the affected skin 1-2 times a day until the effect is obtained. Treatment cannot be carried out for more than 4 weeks without assessing the need for its continuation. For the treatment of exacerbations of skin diseases, repeated short courses of Powercourt can be given. If continued therapy with GCS is needed, less active drugs should be used.
In especially resistant cases, especially in the presence of hyperkeratosis, the anti-inflammatory effect of Powercourt cream can be enhanced by applying a bandage from the PE film overnight to the area of application, which is usually accompanied by a positive effect. In the future, the achieved effect can be maintained without the use of an occlusive dressing.
Side effects
Long-term administration of corticosteroids for local use in large doses or applying them to large areas of the skin may be accompanied by systemic absorption with subsequent development of symptoms of hypercorticism. The risk of developing this complication is increased in children, especially when using an occlusive dressing, while the diaper can play the role of such a dressing.
Subject to the appointment of Powercourt to adult patients at a dosage of not more than 50 g per week, suppression of the pituitary and adrenal gland functions is transient in nature with their rapid recovery immediately after the end of the course of treatment.
Long-term treatment with highly active corticosteroids for topical administration in large doses can cause atrophic changes in the skin, in particular, thinning, the appearance of atrophic strips (striae), expansion of the superficial blood vessels, especially when applying occlusive dressings and when applying the drug to skin areas with folds. Skin pigmentation and hypertrichosis may develop.
In rare cases, treatment of psoriasis of corticosteroids for topical application (or their abolition) provokes the development of pustular psoriasis. Sometimes Powercourt can exacerbate the symptoms of the disease.
Storage Conditions
In a dry, dark place at a temperature not exceeding 25 ° C.
Expiration
2 years.
active substance
Clobetasol
Conditions of release from drugstores
Prescription
lekarstvennaja form
cream
Glenmark Pharmaceuticals Ltd., India
