Description
Latin name
Solcoseryl
release form
ointment
Pharmacological action
Solcoseryl – antihypoxic, cytoprotective, regenerating, membrane stabilizing, angioprotective, wound healing.
The drug Solcoseryl is a deproteinized hemodialysate, containing a wide range of low molecular weight components of the cell mass and blood serum of dairy calves with a molecular weight of 5000 D, the properties of which are currently only partially studied by chemical and pharmacological methods.
In vitro tests, as well as in preclinical and clinical studies, it was found that Solcoseryl:
enhances reparative and regenerative processes
promotes the activation of aerobic metabolic processes and oxidative phosphorylation
increases oxygen consumption in vitro and stimulates glucose transport to cells located in under hypoxia and in metabolically depleted cells,
enhances collagen synthesis (in vitro)
stimulates cell proliferation and migration (in vitro).
Solcoseryl gel does not contain fat as auxiliary components, thanks to which it is easily washed off. Promotes the formation of granulation tissue and the elimination of exudate.
Since the appearance of fresh granulations and drying of the wound, it is recommended to use Solcoseryl ointment, which contains fats as auxiliary components and forms a protective film on the wound surface.
Pharmacokinetics
Studies on the absorption, distribution and excretion of the drug using standard pharmacokinetic methods are not possible, because the active component of the drug (deproteinized hemodialysis) has pharmacodynamic effects characteristic of molecules with different physicochemical properties.
Indications
Minor damage (abrasions, scratches, cuts).
1 and 2 degree burns (sunburn, thermal burns).
frostbite.
Hardly healing wounds (including trophic ulcers and pressure sores).
Contraindications
Hypersensitivity to one of the components of the drug.
Caution – with a predisposition to allergic reactions.
Use during pregnancy and lactation
The use of Solcoseryl, like all other drugs, is undesirable during pregnancy and lactation and is possible only if absolutely necessary and under the supervision of a doctor.
Composition of
1 g of ointment contains:
Active ingredient:
deproteinized dialysate from the blood of healthy dairy calves,
standardized chemically and biologically (in terms of dry matter) 2.07 mg
Excipients: srdlklp
water for injection.
Dosage and administration
Solcoseryl ointment is applied in a thin layer to a cleaned wound 1-2 times a day, can be used under dressings.
The course of treatment with Solcoseryl ointment continues until the wound is completely healed, epithelized and elastic scar tissue forms.
For the treatment of severe trophic injuries of the skin and soft tissues, the simultaneous use of parenteral forms of Solcoseryl is recommended.
Side effects
In rare cases, allergic reactions can develop (urticaria, hyperemia and edema at the injection site, fever).
In this case, stop using the drug and prescribe symptomatic treatment.
Drug Interactions
Saloseril injections should not be mixed with other medicinal products, especially phytoextracts.
Pharmaceutical incompatibility Solcoseril in the form of a solution for injection with parenteral forms has been established:
of Ginkgo biloba extract,
of petroleum furil,
of benziclan fumarate.
Only isotonic sodium chloride solution and 5% glucose solution should be used as solutions for dilution of Solcosyl Injection.
No interaction of Solcoseril with other topical medicinal products has been established.
Storage Conditions
In a dark place at a temperature not exceeding 25 ° C.
Shelf life
5 years.
Deystvuyushtee substance
Deproteinized dialysis from calf blood
dosage form
ointment
Possible product names
SOLKOSERIL 5% 20.0 OINTMENT
Solcoseryl 5% 20g ointment
SOLKOSERIL 5% 20G. OINTMENT
Solcoseryl ointment 20 g
SOLKOSERIL OINTMENT 20G No. 1
Meda Farma GmbH and Ko.KG, Switzerland
