Description
Packing
60 tablets.
Pharmacological action of
Afobazole is a derivative of 2-mercaptobenzimidazole, a selective anxiolytic not belonging to the class of benzodiazepine receptor agonists. Prevents the development of membrane-dependent changes in the GABA receptor.
The drug has an anxiolytic effect with an activating component that is not accompanied by hypnotic effects (sedative effects are detected in doses 40-50 times higher than the ED50 for anxiolytic effects). The drug has no muscle relaxant properties, a negative effect on memory and attention.
When using the drug, drug dependence does not form and withdrawal syndrome does not develop. The action of the drug is implemented mainly in the form of a combination of anxiolytic (anti-anxiety) and easily stimulating (activating) effects.
Reduction or elimination of anxiety (preoccupation, bad feelings, apprehension, irritability), tension (timidity, tearfulness, anxiety, inability to relax, insomnia, fear), and therefore somatic (muscle, sensory, cardiovascular, respiratory, gastrointestinal intestinal symptoms), autonomic (dry mouth, sweating, dizziness), cognitive (difficulty concentrating, impaired memory) disorders are observed on days 5-7 of treatment with Afobazole.
Indications
Anxiety in adults:
generalized anxiety disorders, neurasthenia,
adaptation disorders in patients with various somatic (bronchial asthma, irritable bowel syndrome, SLE, coronary heart disease, arterial hypertension, arrhythmias and other diseases sleep-related anxiety
neurocirculatory dystonia
premenstrual tension syndrome
alcohol withdrawal syndrome
to alleviate withdrawal symptoms in case of failure smoking.
Contraindications
pregnancy
lactation (breastfeeding)
age under 18
hypersensitivity to Afobazole components.
Use during pregnancy and lactation
The drug is contraindicated in pregnancy and lactation (breastfeeding).
Composition
1 tablet contains
morpholinoethylthioethoxybenzimidazole dihydrochloride 10 mg
excipients:
potato starch,
microcrystalline cellulose,
lactose,
lactose, srdl
magnesium stearate.
Side effects
Allergic reactions possible.
Rarely – a headache that usually goes away on its own and does not require discontinuation of the drug.
Overdose
Symptoms: With a significant overdose and intoxication, the development of a sedative effect and increased drowsiness without manifestations of muscle relaxation.
Treatment: as a first aid appoint p / to caffeine-benzoate of sodium 20% solution on 1 ml 2-3 times / days.
Storage conditions
The drug should be stored out of the reach of children, in a dry, dark place at a temperature of no higher than 25 ° C.
Expiration
2 years.
Deystvuyuschee substances
Fabomotyzol
Terms of delivery from pharmacies
Over-the-counter
dosage form well
Dosage form
tablets
Pharmstandard-Leksredstva, Russia
