Description
Latin name
FURASOL
Release form
Powder for preparation for solution for injection.
Packaging
15 sachets.
Pharmacological action
Furasol is an antimicrobial agent derived from nitrofuran. Effective against gram-positive cocci (Staphylococcus spp., Streptococcus spp.), Gram-negative rods (E. coli, Salmonella spp., Shigella spp., Klebsiella spp.). Resistant: Acinetobacter spp., Most strains of Proteus spp., Serratia spp.
The mechanism of action is associated with inhibition of nucleic acid synthesis. Depending on the concentration, it has a bactericidal or bacteriostatic effect. Against most bacteria, the bacteriostatic concentration is 10 20 μg / ml. The bactericidal concentration is about 2 times higher. Under the influence of nitrofurans in microorganisms, there is a suppression of the activity of the respiratory chain and the tricarboxylic acid cycle (Krebs cycle), as well as inhibition of other biochemical processes, which leads to the destruction of their membrane or cytoplasmic membrane. Nitrofurans increase the titer of complement and the ability of leukocytes to phagocytize microorganisms.
Indications
As a topical agent in the complex treatment of the following conditions and diseases: infectious and inflammatory diseases of the oral cavity, oropharynx, infected wounds.
Contraindications
hypersensitivity to furazidine, other components of the drug or preparations of the nitrofuran series
allergic dermatitis
pregnancy
lactation period
age up to 4 years.
Special instructions
The solution is prepared immediately before use. Do not store the prepared solution.
Composition
1 packet with powder for solution for local and external use contains: active ingredient: potassium furazidine 100 mg
excipients: sodium chloride – 900 mg
Dosage and administration
Topically, externally.
The solution is prepared immediately before use. The contents of the bag are dissolved in 200 ml of hot water and a warm solution is used to rinse the mouth and oropharynx 2-3 times a day.
A solution of the drug is also used to wash the wounds after surgical treatment is applied directly to the wound surface, after which a sterile gauze dressing is applied, or on the dressing, and then on the wound. Apply to the wound surface 2-3 times a day.
Side effects
In some cases, allergic reactions may develop. In this case, the use of the drug is stopped. Symptomatic therapy is prescribed.
Drug Interactions
Synergistic in combination with antibiotics. In the case of alcohol during treatment with the drug, the likelihood of developing skin allergic reactions increases.
Overdose
The drug is low toxic. Overdose has not been reported.
Storage Conditions
In a dry, dark place at 15 25 ° C. Keep out of reach of children.
Shelf life
4 years.
Active ingredient substantially the
Furazidin
Dosage form
topical solution
Prescription
Prescription
For children prescribed by a doctor, Adults prescribed by a doctor, Children over 4 years old
Olainfarm, Latvia
