Description
Pharmacological action of
The mechanism of action of fipronil is to block GABA-dependent arthropod receptors, impaired transmission of nerve impulses, which leads to paralysis and death of insects and ticks.
After applying the drug to the skin, fipronil, practically not absorbed into the systemic circulation, spreads over the skin and hair of the animal, accumulates in the epidermis, hair follicles and sebaceous glands, exerting a contact insecticaricidal effect, which manifests itself after 12-24 hours and lasts for 4 -6 weeks after a single treatment of the animal.
DanaВ® Spot-on in terms of its effect on the body refers to low-hazard substances (hazard class 4 according to GOST 12.1.007-76), in recommended doses it does not have skin-irritating, skin-resorptive and sensitizing effect, in contact with eyes causes slight irritation. The drug is toxic to rabbits, bees, as well as fish and other aquatic organisms.
Indications
Assign to dogs and cats from 12 weeks of age for the treatment and prevention of entomoses caused by fleas, lice and lice, acaroses, caused by sarcoptoid, ixodic and demodectic mites, fur animals – for the treatment and prevention of otodectosis.
Contraindications
Contraindication to use is individual intolerance to the components of the drug, including a history of it. Patients with infectious diseases and recovering animals, dogs weighing less than 2 kg, kittens and puppies under the age of 12 weeks cannot be treated. Auricular use of the drug is not allowed (with ear scabies) with perforation of the eardrum. Pregnant and lactating females Dana Spot-on, if necessary, is used under the supervision of a veterinarian.
Special instructions
There are no specific effects of the drug on its first use and withdrawal.
Violations of the regimen of the drug should be avoided, as this may lead to a decrease in its effectiveness. If the next treatment is skipped, it should be carried out as soon as possible, in the same dose.
When using the drug in accordance with these instructions, side effects and complications in animals, as a rule, are not observed. In some animals, with individual hypersensitivity and the appearance of signs of skin irritation and allergic reactions, the drug should be washed off with detergent and, if necessary, carry out desensitizing therapy.
Danu Spot-it should not be used in conjunction with other insecticaricidal drugs for the treatment of animals.
The product is not intended for the treatment of productive animals.
Composition
Fipronil – 50 mg / ml, excipients up to 1 ml.
Side effects of
In rare cases, with increased individual sensitivity to the drug and overdose in animals, excessive salivation, vomiting, muscle tremors and skin irritation may occur. In these cases, the use of the drug is stopped, its residues are carefully removed with a cotton-gauze swab, Wool thoroughly washed with soap and water or shampoo. If necessary, animals are prescribed desensitizing and symptomatic therapy.
topical solution
