Description
Release form
1 Contains fipronil and S-metoprene as active ingredients.
Fipronil is an insecticide of the phenylpyrazole group, the mechanism of contact action is to block GABA-dependent arthropod receptors, impaired transmission of nerve impulses, which leads to paralysis and death of ectoparasites.
Metoprene – an analogue of juvenile hormone, an insect growth regulator disrupting chitin synthesis, causes anomalies in the development of insects at the egg and larva stage, prevents the appearance of sexually mature insects on animals and in their places of detention.
Fiprist Combo is active against fleas (mature and preimaginal phases of development) Ctenocephalides spp. tongs Felicola subrostratus, Trichodectes canis ticks (all phases of development) Dermacentor variabilis, Rhipicephalus sanguineus, Ixodes scapularis, lxodes ricinus, Ixodes holocyclus, Haemaphysalis longicornis, Haemaphysalis flava, Haemaphysalis campanulata, Haemaphysalis leachi, Amblyomma americanum mosquito Aedes aegypti sarkoptoidnyh mite Sarcoptes scabiei var . canis.
After application to the skin, the active substances are gradually distributed over the entire surface of the animal’s body for 24 hours, practically not absorbed into the systemic circulation, accumulate in the epidermis, hair follicles and sebaceous glands, have a long contact effect, protecting the animal from ectoparasites.
A single treatment of the animal ensures the destruction of fleas and ticks within 24 and 48 hours, respectively. The protective effect of the drug against ixodid ticks continues in cats and ferrets – up to 4 weeks against the adult and preimaginal phases of insect development in cats and ferrets – up to 6 weeks.
Fiprist Combo by its degree of exposure to the body refers to moderately hazardous substances (hazard class 3 according to GOST 12.1.007-76), at the recommended doses it does not have a skin-irritating, resorptive-toxic, embryotoxic and teratogenic effect, if it gets into the eyes it causes a slight irritation. The drug is toxic to rabbits, as well as fish and other aquatic organisms.
Indications
Fiprist Combo is prescribed for cats and ferrets:
– for the treatment and prevention of entomoses caused by fleas, lice and lice eaters
– for the treatment and prevention of acaroses caused by Ixodes ticks
– in the treatment of allergic dermatitis attachment and development of ectoparasites in animals.
Recommendations for use
Fiprist® Combo is applied to animals once by topical application (spot-on) to dry intact skin using pipettes of various packaging. Before processing, the tip of the pipette is punctured with an inverted cap, the animal’s fur is spread in the back (between the shoulder blades) and, by pressing the pipette, the preparation is applied to the skin at the withers at one or more points in a minimum dose of 0.067 ml / kg, according to the table.
Type of animal pipette volume and label on the package content of active ingredients in 1 pipette
Fipronil, mg S-metoprene, mg
Cats, ferrets 0.5 ml 50 60
Avoid contact with the eyes of the animal. It is necessary to make sure that the preparation is applied to the animal on an area of the body that is inaccessible for licking. Do not allow animals living together to lick each other until the drug completely dries.
Do not wash or bathe animals with detergents, keep animals in natural water for 48 hours after treatment, and apply the product on wet or damaged skin.
Repeated treatment of animals is carried out according to indications, but not more often than 1 time in 4 weeks. In order to prevent re-infestation of animals with fleas, it is recommended to treat all animals living together, as well as replace litter or treat them with an insecticidal agent in accordance with the instructions for its use.
Peculiarities of the action of the drug during the first use and withdrawal were not detected. A wet or oily stain may be noted on the animal’s coat for 24 hours after application.
Violations of the drug regimen should be avoided, as this may lead to a decrease in its effectiveness. If the next treatment is skipped, it should be carried out as soon as possible in the same dose.
Composition
The solution for external use (for cats and ferrets) is transparent, yellow in color, without particles.
1 ml 1 pipette
fipronil 100 mg 50 mg
S-metoprene 120 mg 60 mg
Excipients: povidone K25, polysorbate 80, butylhydroxyanisole (E320), butylhydroxytoluene (E321), ethylene ethanol, ethylene 1 ml
dosage form
solution topical application
