Description
Latin name
DONA
Release form
3950 mg (1500 mg glucosamine sulfate) in sachets of a three-layer material made of paper, polyethylene, sealed together thermally from four sides.
The plastic film is in direct contact with the contents of the bag.
20 sachets together with instructions for use are placed in a cardboard box.
Pharmacological action of
Pharmacological properties of
DONA has an anti-inflammatory and analgesic effect, compensates for endogenous glucosamine deficiency, stimulates the synthesis of proteoglycans and hyaluronic acid in synovial fluid, increases the permeability of the joint capsule, and restores the enzymatic processes in the synovial membrane of the cell. It promotes the fixation of sulfur during the synthesis of chondroitin sulfuric acid, facilitates the normal deposition of calcium in bone tissue, inhibits the development of degenerative processes in the joints, restores their function, reducing joint pain.
Pharmacokinetics
Absorption in the gastrointestinal tract 90%, bioavailability 26%, half-life 70 hours.
Indications
Primary and secondary osteoarthritis, osteochondrosis, spondylarthrosis.
Contraindications
Individual hypersensitivity to glucosamine sulfate, aspartame and other components of the drug. Due to the content of aspartame, it is contraindicated in patients with phenylketonuria.
It is not recommended to prescribe the drug during pregnancy and lactation, as well as in childhood (up to 12 years) due to the lack of scientific clinical data in this category of patients.
Special instructions
Caution is advised for patients with allergies to seafood (shrimp, mollusks).
When using the drug in patients with impaired glucose tolerance, with severe hepatic and renal failure, medical supervision is necessary.
Composition
One sachet contains:
active substance: crystalline glucosamine sulfate 1884 mg (contains glucosamine sulfate 1500 mg and sodium chloride 384 mg)
excipients: aspartame, sorbitol, carbovax 4000 (macrogol 4000), citric acid.
Dosage and Administration
Inside. The contents of one sachet are dissolved in 200 ml of water, taken orally 1 time per day. Symptomatic effect occurs 2-3 weeks after the use of the drug. The duration and treatment regimen is prescribed by the attending physician. The minimum course of therapy is 6 weeks.
Side effects
Tolerance to the drug is good, in some cases are possible: gastralgia, flatulence, diarrhea, constipation, allergic reactions – urticaria, itching.
Drug Interactions
Compatible with non-steroidal anti-inflammatory drugs, paracetamol and glucocorticosteroids. Increases the absorption of tetracyclines, decreases – semisynthetic penicillins, chloramphenicol.
Overdose
Cases of overdose unknown. Treatment: gastric lavage, symptomatic therapy.
Storage Conditions
Do not store above 25 C. Keep out of the reach and sight of children.
Expiration
3 years. Do not use after the expiry date stated on the packaging.
lekarstvennaja form
Solution for pryema inside
Rottafarm46
