Description
Release form
Tablets
Packaging
50 units
Pharmacological action of
Pharmacodynamics of
The spectrum of action is associated with the presence of gamma-aminobutyric acid in the structure. The mechanism of action is due to the direct effect of pantocalcin on the GABAB receptor-channel complex. It has neurometabolic, neuroprotective and neurotrophic properties. Increases brain resistance to hypoxia and the effects of toxic substances, stimulates anabolic processes in neurons. It has an anticonvulsant effect, reduces motor excitability while streamlining behavior. Increases mental and physical performance
. Helps to normalize the content of gamma-aminobutyric acid in chronic alcohol intoxication and the subsequent abolition of ethanol. It has an analgesic effect. It is able to inhibit acetylation reactions participating in the mechanisms of inactivation of novocaine and sulfonamides, due to which the prolongation of the action of the latter is achieved. Causes inhibition of pathologically increased cystic reflex and detrusor tone.
Pharmacokinetics
Rapidly absorbed in the gastrointestinal tract. The time to reach maximum plasma concentration is 1 hour.
The highest concentrations are created in the liver, kidneys, stomach wall, and skin. Penetrates through the blood-brain barrier. Not metabolized. It is excreted unchanged for 48 hours (67, 5% of the dose taken – with urine, 28.5% – with feces).
Indications
Cognitive impairment in organic brain damage and neurotic disordersParkinson s disease)
consequences of neuroinfections and traumatic brain injuries (as part of complex therapy)
correction and prevention (cover therapy with simultaneous prescribing) side effects of antipsychotics extrapyramidal neuroleptic syndrome (hyperkinetic and akinetic)
epilepsy with slowdown anticonvulsants)
psycho-emotional overload, decreased mental and physical performance to improve concentration and commemoration
urination disorders: enuresis, daytime urinary incontinence, pollakiuria, imperative urge
Children:
mental retardation (mental retardation, speech, motor development or a combination thereof)
cerebral palsy
stuttering (mainly clonic form)
epilepsy (as part of combination therapy with anticonvulsants, especially for polymorphic seizures and small seizures).
Contraindications
Hypersensitivity
acute renal failure
pregnancy (1 trimester).
Use during pregnancy and lactation
Contraindicated in the first trimester of pregnancy.
Special instructions
Do not use after the expiration date.
Composition
Active ingredient:
calcium hopantenate (hopantenic acid or calcium salt of hopantenic acid) 0, 5 g (500 mg)
Excipients:
magnesium hydroxycarbonate 93.54 mg
calcium stearate 6.2 mg
talcum 12.4 mg
potato starch 7.86 mg
Side effects
Allergic reactions (rhinitis, conjunctivitis, skin rashes) are possible.
Drug interaction
prolongs the action of barbiturates enhances the effects of drugs that stimulate the central nervous system, anticonvulsants, the effects of local anesthetics (procaine).
Prevents side effects of the following drugs: phenobarbital, carbamazepine, antipsychotics (antipsychotics).
The effect of hopantenic acid is enhanced in combination with glycine, xidiphone.
Overdose
Increased severity of side effects.
Treatment: gastric lavage, administration of activated charcoal, symptomatic therapy.
Storage conditions
Out of reach of children, dry, protected from light at a temperature up to 25 ° C
Shelf life
4 years
Deystvuyushtee substance
Gopantenovaya Chisloth
Terms and conditions
prescription
dosage form
tablets
Possible product names
PANTOCALCIN 0.5 N50 TABL
Pantocalcin 500 mg tab. X50
PANTOCALCIN 500MG. No. 50 TAB.
Pantocalcine tab 500mg N50 (pack N10x5)
Pantocalcine tab 500mg x 50
