inosine pranobex – Isoprinosine tablets 500 mg 30 pcs

$30.00

Description

Latin name

ISOPRINOSINE

Release form

Tablets are white or almost white, oblong, biconvex, with a slight amine odor, with a risk on one side.

packaging 10 pcs – blisters (3) – packs of cardboard.

Indications

Treatment of influenza and other acute respiratory viral infections caused by Herpes simplex virus of the 1st, 2nd, 3rd and 4th types: genital and labial herpes, herpes keratitis, herpes zoster, chickenpox, infectious mononucleosis caused by Epstein-Barr virus, cytomegalovirus infection, severe measles, papillomavirus infection: larynx / vocal cord papillomas (fibrous type), genital papillomavirus infection in men and women, molluscum contagiosum warts.

Contraindications

Hypersensitivity to the components of the drug.

Gout, urolithiasis, chronic renal failure, arrhythmias, pregnancy, breastfeeding, children under 3 years old (body weight up to 15-20 kg).

Use during pregnancy and lactation

Use during pregnancy and lactation (breastfeeding) is contraindicated.

Composition of

One tablet contains:

Active ingredient:

Inosine Pranobex (Isoprinosine) – 500 mg

Excipients:

mannitol,

wheat starch,

povidone magnesium,

povidone magnesium.

Dosage and administration

Tablets are taken orally after a meal with a little water.

The recommended dose for adults and children from 3 years of age (body weight from 15-20 kg) is 50 mg / kg per day, divided into 3-4 doses. For adults – 6-8 tablets per day, for children – for? tablets at 5 kg / body weight per day. In severe forms of infectious diseases, the dose can be individually increased to 100 mg / kg body weight per day, divided into 4-6 doses.

The maximum daily dose for adults is 3-4 g / day, for children – 50 mg / kg / day.

Duration of treatment

Acute illness: The duration of treatment in adults and children is usually 5 to 14 days. Treatment should be continued until the disappearance of clinical symptoms and for another 2 days already in the absence of symptoms. If necessary, the duration of treatment can be increased individually under the supervision of a physician.

In chronic relapsing diseases in adults and children, treatment should be continued with several courses of 5-10 days with a break in admission of 8 days.

For maintenance therapy, the dose can be reduced to 500-1000 mg per day (1-2 tablets) for 30 days.

For herpetic infections, adults and children are prescribed for 5-10 days before the symptoms disappear, in the asymptomatic period, 1 tablet 2 times a day for 30 days to reduce the number of relapses.

In case of human papillomavirus infection, the drug is prescribed 2 tablets 3 times a day, for children -? tablets of 5 kg / body weight per day in 3-4 doses for 14-28 days in the form of monotherapy. With recurrent genital warts, for adults, the drug is prescribed 2 tablets 3 times, for children -? tablets at 5 kg / body weight per day in 3-4 doses per day, either as monotherapy or in combination with surgical treatment for 14-28 days, then with a triple repetition of the indicated course at intervals of 1 month.

In case of cervical dysplasia associated with human papillomavirus, 2 tablets are prescribed 3 times a day for 10 days, then 2-3 similar courses are carried out with an interval of 10-14 days.

Side effects

From the nervous system: often – headache, dizziness, fatigue, poor health infrequently – nervousness, drowsiness, insomnia.

From the gastrointestinal tract: often – decreased appetite, nausea, vomiting, epigastric pain infrequently – diarrhea, constipation.

From the hepatobiliary system: often – increased activity of liver enzymes, alkaline phosphatase.

From the skin and subcutaneous fat: often – itching, rash.

From the kidneys and urinary tract: infrequently – polyuria.

Allergic reactions: infrequently – maculopapular rash, urticaria, angioedema.

From the musculoskeletal system: often – joint pain, exacerbation of gout.

Other: often – increased blood urea nitrogen concentration.

Drug Interaction

Immunosuppressants attenuate the immunostimulatory effect of pranobex inosine.

When co-administered with xanthine oxidase inhibitors (allopurinol) or loop diuretics (furosemide, torasemide, ethacrynic acid), uric acid concentration in the serum may be increased.

Co-administration with zidovudine increases the concentration of zidovudine in blood plasma and lengthens it with T1 / 2. This combination may require a dose adjustment of zidovudine.

When combined, increases the effect of interferon-alpha, acyclovir and zidovudine antiviral agents.

Overdose

Isoprinosine overdose has not been reported.

Storage conditions

List B. The drug should be stored out of the reach of children, in a dry, dark place at a temperature not exceeding 25 ° C.

Expiration

5 years.

Deystvuyuschee substances

inosine pranobex

Dosage form

dosage form

tablets