Description
Latin name
FASTUM ®
Release form
Gel for external use 2.5%.
Packing
50 g in a tube.
Pharmacological action
Pharmacodynamics
NSAIDs for external use. The mechanism of action is associated with inhibition of prostaglandin synthesis. It has a local analgesic, anti-inflammatory, antiexudative effect.
With the symptomatic treatment of diseases of the joints, tendons, ligaments, muscles, skin with the joint syndrome, it reduces joint pain at rest and during movement, morning stiffness and swelling of the joints.
Pharmacokinetics
When applied topically, it is absorbed extremely slowly. Bioavailability is 5%. When used in a dose of 50-150 mg, the concentration in the blood plasma is 0.08-0.15 μg / ml. Does not cumulate in the body.
Indications
Diseases of the musculoskeletal system (joint syndrome with exacerbation of gout, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, osteoarthritis, osteochondrosis with radicular syndrome, inflammatory lesions of the ligaments, tendons, bursitis, sciatica, lumbago)
myalgia of rheumatic and non-rheumatic origin
post-traumatic inflammation of the soft tissues and musculoskeletal system.
Contraindications
Soaking dermatoses, eczema, infected abrasions,
wounds, a history of bronchospasm, urticaria, or rhinitis due to the use of acetylsalicylic acid
children under 12 years of age
III trimester of pregnancy
lactation (breastfeeding)
increased sensitivity to other drugs, acid.
Use with caution in: erosive and ulcerative lesions of the gastrointestinal tract, severe impaired renal and hepatic function, chronic heart failure, bronchial asthma, and liver porphyria.
Use during pregnancy and lactation
The drug is contraindicated for use in the III trimester of pregnancy and during lactation (breastfeeding). In the I and II trimesters, the drug is used with caution.
Composition of
100 g of gel contain:
Active ingredients:
ketoprofen 2.5 g
Excipients:
carbomer 940 – 1.5 g,
ethanol 96% – 40 ml,
nerolium oil – 0.05
lavender oil (hybrid lavender oil).
Dosage and administration
The drug is intended for external use.
A small amount of gel (3-5 cm long column) is applied 1-2 times / day with a thin layer on the skin over the site of inflammation and rubbed lightly.
The duration of treatment should not exceed 14 days.
Side effects
Local reactions: allergic dermatitis, eczema, flushing of the skin, photodermatitis, bullous dermatitis, exanthema, purpura.
Systemic reactions: urticaria, generalized skin rash, edema, photosensitivity, stomatitis.
Drug Interaction
The interaction of Fastum with other medicines has not been described.
overdose
Due to extremely low systemic absorption, overdose is unlikely.
Storage conditions
Store in a dark place and out of the reach of children at a temperature of 15 ° to 25 ° C.
Expiration
5 years.
Deystvuyuschee substance Ketoprofen
Dosage form
Dosage form srd lkp gel for external use
Berlin-Chemie / Menarini Germany
