Description
Release form
Film-coated tablets.
Packing
20 pcs.
Pharmacological action
Pharmacodynamics. Antispasmodic with selective action on the gastrointestinal tract. Inhibits the entry of calcium into the cells of the smooth muscles of the intestine. Animal studies have shown that pinaveria bromide reduces the effects of stimulation of sensitive neurons. It does not have an anticholinergic effect. It does not affect the cardiovascular system.
Pharmacokinetics. After oral administration of pinaveria, bromide is rapidly absorbed and reaches a maximum plasma concentration after one hour. Pinaveria bromide has a high ability to bind to plasma proteins (95-96%). The drug is actively metabolized in the liver. The half-life is 1.5 hours. The absolute bioavailability is very low (less than 1%). It is excreted mainly with feces.
Indications
spasms of the smooth muscles of the abdominal cavity: dyskinesia of the colon, biliary dyskinesia
preparation for X-ray examination of the gastrointestinal tract using barium.
Contraindications
hypersensitivity,
paralytic bowel obstruction,
intestinal atony,
toxic megacolon,
severe ulcerative colitis.
Use during pregnancy and lactation
During pregnancy and lactation (breastfeeding) Ditetel is prescribed only in cases where the intended benefits to the mother outweigh the potential risk to the fetus or baby.
Special instructions
Dietitel is prescribed for children only in cases where the intended benefit outweighs the potential risk.
Composition
1 film-coated tablet contains:
Active ingredient: pinaveria bromide – 50 mg.
Excipients: colloidal silicon dioxide – 1.00 mg, microcrystalline cellulose – 79.35 mg, talc – 3.00 mg, magnesium stearate – 1.50 mg, pregelatinized starch – 17.00 mg, lactose monohydrate – 18.15 mg.
Film coating: basic butyl methacrylate – 8.176 mg, sodium lauryl sulfate – 0.818 mg, talc – 6.473 mg, stearic acid – 1.192 mg, dry sepispers 3203 – 0.341 mg (hypromellose (E 464) – 55.0-65.0%, microcrystalline cellulose (E 460) – 5.015.0%, titanium dioxide (E 171) – 20.0-30.0%, sunset sunset dye yellow (aluminum varnish) (E 110) – 3.0%).
Dosage and administration of the
Dietel is prescribed for adults.
coated tablets (containing 50 mg pinaveria bromide), 3-4 tablets per day are prescribed, if necessary (in exceptional cases), a dose increase of up to 6 tablets / day is possible.
Dietetel tablets containing 100 mg of pinaveria bromide are prescribed 1 tablet 2 times a day (morning and evening).
If necessary (in exceptional cases), the dose can be increased to 3 tablets per day
Side effects
From the digestive system: rarely – dyspepsia, constipation, nausea.
Other: rarely – allergic reactions.
Overdose
Symptoms: An overdose can lead to gastrointestinal upsets, such as flatulence and diarrhea.
Treatment: specific antidote unknown symptomatic treatment recommended.
Storage Conditions
In a dry, dark place at a temperature not exceeding 30 ° C.
Expiration
5 years.
active substance
pinaverium bromide
Conditions prescription pfroaf ska through pharmacies
In retseptu
The dosage form of
tablet
Prescribing
Adults as prescribed by the doctor, For pregnant women as prescribed by the doctor
Indications
Indications
From dysbacteriosis, 6, from dysbacteriosis, 6, dysbacteriosis,
From biliary dyskinesia, To prepare for an ultrasound and x-ray of the abdominal cavity, From gastrointestinal spasms
