Description
Pharmacological action
Stop-Intim tablets for cats are hormonal drugs.
Megestrol acetate, which is part of the drug, is a synthetic derivative of the hormone progestogen, has the property to inhibit the secretion of luteinizing (LH) and follicle-stimulating (FSH) hormones, which are produced by the anterior pituitary gland. When using the drug before the onset of estrus (estrus), the synthesis of estrogen by the ovarian follicles is inhibited, which prevents the development of morphological and psychophysiological changes in females associated with the sexual cycle. When using the drug for females on 2 or 3 days from the start of estrus, estrus is interrupted.
In males of megestrol, acetate reduces testosterone levels in the blood and has an indirect effect on the regulation of sexual behavior and related behavioral reactions, reducing aggression, anxiety and increased excitability in the animal.
Megestrol acetate is easily adsorbed in the intestine, biotransformed in the liver and excreted in the form of salts with urine within 1 – 2 days.
Stop-Intim tablets for cats are classified as low-hazard substances according to the degree of exposure to the body (hazard class 4 according to GOST 12.1.007-76), at the recommended doses they do not have hepatotoxic, mutagenic and sensitizing effects.
Indications
op-Intimacy tablets for cats are prescribed to regulate sexual hunting in cats, including to delay and interrupt estrus in female cats, reduce sexual activity and correct behavior in cats.
Contraindications
Contraindication to the use of Stop-Intim tablets for cats is an increased individual sensitivity of the animal to the components of the drug (including a history), diseases of the genitourinary system, tumors and diabetes.
Composition
Stop-Intim tablets for cats contain 5 mg of megestrol as an active ingredient in acetate, as well as excipients: microcrystalline cellulose, lactose, calcium stearic acid, sodium starch glycolate (type A) and crospovidone.
Dosage and administration of
Stop-Intim tablets for cats are administered orally, forcibly to the root of the tongue, 1 to 2 hours before feeding, taking into account the testimony and gender of the animal.
In order to delay estrus for cats, the drug is used between the estrus once a week at a dose of 1/2 tablet or once every two weeks at a dose of 1 tablet (5 mg DV), but not more than 18 consecutive months. Repetition of the course is possible after the manifestation of a normal physiological cycle in a cat.
In order to interrupt estrus to cats, the drug is used when its first signs appear (but no later than 3 days after its start) at a dose of 1 tablet (5 mg DV) per animal 5-7 times a day with an interval of 24 hours (until disappearance) signs of estrus plus one day).
Kotam is used in a dose of 1 tablet (5 mg DV) per animal to reduce sexual arousal and correct behavior.
The first 7 days, the drug is given daily in a daily dose, the next 14 days – 1/2 daily dose.
Storage conditions
Store the drug in the manufacturer s sealed packaging, in a place protected from direct sunlight, separately from food and feed, at a temperature of 2 ° C to 25 ° C.
active substance
Megestrol
