Description
Pharmacological action of
Fipronil has a pronounced contact insecto-acaricidal effect against ectoparasites of dogs: lice, fleas, lice, ticks, as well as cheilitiella and the causative agent of ear scabies. The mechanism of action of fipronil is to block the GABA-dependent receptors of the parasite, in violation of the transmission of nerve impulses, which ultimately leads to paralysis and death of the parasites. Fipronil has no effect on mammalian GABA receptors. When applied to the skin of an animal, the drug is practically not absorbed and is evenly distributed over the surface of the body during the day, accumulating in the sebaceous glands of the skin, while providing a long insect-acaricidal effect. Front Line Spot It is classified as a low-hazard substance in terms of its effect on the organism of warm-blooded animals and does not have a resorptive-toxic, sensitizing, embryotoxic, teratogenic and mutagenic effect in recommended doses. Eye contact causes slight irritation.
Indications
Assign to dogs weighing 20 to 40 kg against ectoparasites: fleas, lice, lice, ixodid ticks, and heletiella. For the treatment of otodectosis (ear scabies) in animals.
Contraindications
Increased individual sensitivity to the components of the drug. Puppies under the age of 8 weeks are not to be processed.
Special instructions
When handling the product, it is recommended to use rubber gloves, especially if there are abrasions on the hands and other skin lesions. During processing, it is forbidden to drink, smoke and eat food. Do not stroke the animal and let it in to small children within 24 hours after using the drug. If the product accidentally gets on the skin or mucous membranes, it must immediately be washed off with a stream of water or removed with a swab and then washed with water. At the end of the treatment, hands should be thoroughly washed with warm water and soap.
Composition
Frontline Spot It contains fipronil (chemical formula: C12H4CL2F6N4OS) in 10% concentration as an active ingredient, as well as excipients and solvents.
Dosage and administration
Front Line Spot It is applied topically by topical (spot) application to the skin. Before processing, the tip is broken off at the pipette and the animal s fur is spread in the back (between the shoulder blades) and, pressing the pipette, completely squeeze its contents onto the skin at one or several points. If the animal weighs about 40 kg, then a dog dropper from 40 to 60 kg should be used. The protective effect of the drug against ticks is 1 month, against insects – 2 – 2.5 months. For the treatment of otodectosis (scabies), the ear canal is cleaned of crusts and scabs and 4-6 drops of the drug are instilled into both ears, even if only one ear is affected. For an even distribution of the drug, the auricle is folded in half and lightly massaged at the base, and the remainder of the drug can be applied to the skin between the shoulder blades. Processing is carried out once. In advanced cases of otodectosis complicated by otitis media, antibacterial and anti-inflammatory drugs are prescribed. The drug can be used in pregnant and lactating bitches. You can wash animals with shampoo no earlier than 48 hours after treatment.
Side effects of
Allergic reactions are possible in hypersensitive animals. In these cases, the use of the drug is stopped, the remaining product on the skin is removed with a cotton swab and washed with water, if necessary, carry out desensitizing therapy.
Storage conditions
Precautions. In the manufacturer s packaging, in a dry, dark place and out of the reach of children and animals. Separated from food and feed at temperatures from 0 to 35 ° C.
Shelf life
3 years.
Active ingredient
fipronil
Dosage form
solution for external use
