Description
Pharmacological action
Scope – orthopedics, rheumatology, traumatology, surgery, sports medicine. Armaviscon is a protector of synovial fluid of the joint. It is used against the background of degenerative changes in the surface of the synovial cartilage to improve joint mobility, reduce pain, reduce inflammatory reactions and restore homeostasis in cartilage.
Properties and effectiveness of
The product has an analgesic, corrective effect on the metabolism of bone and cartilage. Armaviscon is a sterile viscous solution of the sodium salt of hyaluronic acid (sodium hyaluronate) with a high degree of purification, high molecular weight.
Hyaluronic acid – a necessary component of the extracellular matrix, is present in high concentrations in the composition of cartilage and synovial fluid. Hyaluronic acid provides the viscosity and elasticity of the synovial fluid, and it is also necessary for the formation of cartilage. With osteoarthritis, deficiency and qualitative changes in hyaluronic acid in the composition of synovial fluid and cartilage are noted.
Intra-articular administration of hyaluronic acid leads to an improvement in the functional state of the joint. When using Armaviscon ® for osteoarthritis of the knee joint, an improvement in the clinical course of 2 osteoarthritis up to six months from the time of application is noted, an anti-inflammatory and analgesic effect is observed due to replenishment of the volume and restoration of the viscosity and elasticity of the synovial fluid, which fills the joint cavity and acts as an intraarticular lubricant.
It prevents friction of the articular surfaces, which eliminates pain and inflammation. It also protects against premature wear and destruction of hyaline cartilage, provides mobility, and has cushioning capabilities (dampens external shocks, protecting joint components from damage).
Hyaluronate sodium solution is distributed topically in the joint cavity, where it undergoes local transformations, providing a lubricating effect. Removing or replacing the product is not applicable, since it is inextricably mixed with synovial fluid of the joint.
Indications
for increasing joint mobility and eliminating pain caused by degenerative-dystrophic or post-traumatic joint changes
for rehabilitation after
arthroscopy for the treatment of patients with increased physical activity and regularly loading the affected joint.
Contraindications
hypersensitivity to the components of
means the presence of infection or damage to the skin at the injection site
acute synovitis
children under 18 years of age (due to lack of clinical data).
Special instructions
Sodium hyaluronate obtained by fermentation of bacteria Streptococcus equi and thoroughly cleaned. However, the doctor must consider the potential risk associated with the injection of any biological substance.
Extraarticular injection of Armaviscon into a joint capsule or synovial tissue is not permitted. This can cause local side effects. It is unacceptable for the product to enter the blood vessels.
During the first 2 days after the procedure, it is recommended not to overload the joint, especially prolonged loading should be avoided. Armaviskon does not affect a person ² ¢s ability to drive vehicles, engage in other potentially dangerous activities that require an increased concentration of attention and speed of psychomotor reactions. Patients with inflammatory diseases, in particular, with ankylosing spondylitis and rheumatoid arthritis, Armaviskon is not prescribed.
Not intended for children. For single use only. The kit may include 2 sterile disposable injection needles for the doctor to select the required size of needle, depending on the joint into which the product will be inserted. For safe use and disposal of used needles, comply with national and regional rules and regulations.
Composition
Composition per 1 ml:
sodium hyaluronate – 9-11 mg / ml (1%),
sodium chloride – 8.50 mg / ml,
sodium hydrogen phosphate dihydrate – 0.28 mg / ml,
sodium dihydrogen phosphate dihydrate – 0.044 mg / ml,
water for injection – up to 1 ml.
Side effects
Mild pain, swelling, fever and redness in the injection area, increased exudate in the joint cavity may occur.
The above symptoms are transient and usually disappear after 24 hours.
When these symptoms occur, it is recommended to relieve the affected joint and apply ice. Very rarely, allergic reactions can be observed.
Storage conditions
Store at a temperature of + 2 ° C to + 25 ° C.
Do not freeze.
Keep out of the reach of children.
Shelf life
3 years. Do not use after expiration date!
active substance
sodium hyaluronate
Dosage form
solution for injection
