Description
Latin name srdlROPfDLER 50 Lrd 50 Lrd THRDLER 50 PER 50
Main physicochemical properties: transparent viscous solution without visible impurities.
Pharmacological action
Agents, used in the pathology of the musculoskeletal system.
Indications
Traumatic and degenerative joint pathology. Auxiliary for orthopedic surgery.
Contraindications
Individual hypersensitivity to the components of the drug. The presence of a history of allergy to poultry proteins. Severe impairment of liver function.
Intra-articular injections are contraindicated in case of existing infection or skin diseases at the injection site in order to reduce the potential development of septic arthritis.
Special instructions
Disinfectants containing quaternary ammonium salts are not recommended, since contact with hyaluronic acid may result in
precipitate intra-articular injection should be carried out by competent medical personnel in accordance with the established procedure under aseptic conditions necessary for this method of application.
Some patients with inflammatory arthritis (rheumatoid arthritis or gouty arthritis) experienced a transient increase in inflammation after drug injection.
In the presence of an articular effusion, it is recommended to perform aspiration before the introduction of Hialubriks.
It is recommended not to overload the joint for several hours after the injection.
Use during pregnancy or lactation.
Although no embryonic toxicity or teratogenic effects were observed in animal experiments, the use of the drug for pregnant women and mothers who are breastfeeding should be limited, except in cases that, according to the doctor ² ¢s assessment, were absolutely necessary, and only after a careful assessment of the risk / benefit ratio.
Composition
Active ingredient: hyaluronic acid
2 ml of the solution contains 30 mg of sodium salt of hyaluronic acid.
Excipients: sodium chloride sodium dihydrogen phosphate, sodium hydrogen phosphate dihydrate, dodecahydrate water for injection.
Dosage and administration of
Adults prescribe 2 ml of the drug by intra-articular administration once a week for 3 weeks.
Children.
Do not use.
Side effects
Reactions at the injection site, including discomfort, pain, swelling, redness, irritation, rashes, nodules, pustules, vesicles, hemorrhages, ecchymosis, itching, joint inflammation, synovitis, joint effusion, joint stiffness, impaired mobility. These symptoms disappear within a few days if you allow the joint to rest and attach an ice pack. Only in rare cases, such reactions were longer and more serious.
Hypersensitivity reactions, including anaphylactoid reactions, angioedema, skin reactions, including rash, itching, erythema, eczema, dermatitis, urticaria, very rarely – anaphylactic shock, but without fatal consequences, serum sickness fever, sensation of fever, headache, paresthesia.
If the patient has a chronic inflammatory process in the acute stage, the use of hyaluronic acid in some individual cases worsened the patient’s condition.
There have been cases of bacterial arthritis and reactive arthritis at the site of intra-articular injection.
Drug Interactions
Hyaluronic acid interacts with some local anesthetics, prolonging their analgesic effect.
Overdose
The phenomena associated with overdose cases are currently not recorded.
Storage conditions
Store in the original packaging, out of the reach of children, at a temperature not exceeding 25 ° C.
30 months.
Deystvuyuschee substances
Hyaluronat sodium
Conditions of supply of
Pharmacy Prescription
Form of Treatment
simply entails dlya inaektsiy
